Studying the protein expression in human B lymphoblastoid cells exposed to 1.8-GHz (GSM) radiofrequency radiation (RFR) with protein microarray.
Zhijian C, Xiaoxue L, Wei Z, Yezhen L, Jianlin L, Deqiang L, Shijie C, Lifen J, Jiliang H. · 2013
View Original AbstractCell phone radiation altered 27 proteins controlling DNA repair and cell death at legal exposure limits, suggesting potential cellular damage mechanisms.
Plain English Summary
Researchers exposed human immune cells to cell phone radiation (1.8 GHz) for 24 hours. They found significant changes in 27 proteins involved in DNA repair and cancer prevention, suggesting that cell phone-level radiation may disrupt cellular processes that protect against genetic damage.
Why This Matters
This study provides molecular-level evidence that radiofrequency radiation at levels comparable to cell phone use can alter fundamental cellular processes. The 2.0 W/kg SAR exposure used here is right at the legal limit for cell phones in many countries, making these findings directly relevant to everyday exposure. What makes this research particularly significant is its focus on proteins that control DNA repair and programmed cell death - cellular mechanisms that, when disrupted, can contribute to cancer development. The fact that 27 different proteins showed altered expression patterns suggests widespread cellular stress responses to RF radiation. While this is laboratory research on isolated cells rather than whole organisms, it adds to a growing body of evidence that RF radiation can trigger biological changes at the molecular level, even at legally permitted exposure levels.
Exposure Details
- SAR
- 2 W/kg
- Source/Device
- 1.8-GHz
- Exposure Duration
- 24 hours
Exposure Context
This study used 2 W/kg for SAR (device absorption):
- 5x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
The Aim of this study is to investigate Studying the protein expression in human B lymphoblastoid cells exposed to 1.8-GHz (GSM) radiofrequency radiation (RFR) with protein microarray.
In the present study, the protein microarray was used to investigate the protein expression in human...
The differential expression of 27 proteins was found, which were related to DNA damage repair, apopt...
Because of the crucial roles of those proteins in DNA repair and cell apoptosis, the results of present investigation may explain the biological effects of RFR on DNA damage/repair and cell apoptosis.
Show BibTeX
@article{c_2013_studying_the_protein_expression_1469,
author = {Zhijian C and Xiaoxue L and Wei Z and Yezhen L and Jianlin L and Deqiang L and Shijie C and Lifen J and Jiliang H.},
title = {Studying the protein expression in human B lymphoblastoid cells exposed to 1.8-GHz (GSM) radiofrequency radiation (RFR) with protein microarray.},
year = {2013},
url = {https://pubmed.ncbi.nlm.nih.gov/23454122/},
}