Effects of wireless local area network exposure on testicular morphology and VEGF levels Çakmak E et al. · 2026
VEGFA gene expression and protein levels increased significantly in the exposed group while HIF1A gene expression did not change. Exposed rats had reduced seminiferous tubule diameter, epithelial thickness, tubule density, and Sertoli cell count.
Bektas H, Yildirim S, Cakir S, Dogu S, Altindag F · 2026
Twenty-eight adult male Wistar rats were divided into Control, RF, CoQ10, and RF + CoQ10 groups. RF exposure lowered testosterone, LH, and FSH, raised MDA and TOS, and produced degenerative testicular changes; CoQ10 partially reversed these changes by restoring testosterone and TAS and reducing tissue damage.
Unknown authors · 2025
EMR exposure caused marked structural damage to seminiferous tubules, increased collagen deposition, expanded tubular and interstitial volumes, raised IL-6 and TNF-α expression, and reduced antioxidant enzyme activities while increasing MDA levels. Alpha-lipoic acid supplementation prevented the structural damage, lowered inflammatory markers, restored AR, ZO-1, and ZO-2 expression, and reversed the oxidative stress parameters.
Zhaowen Z et al. · 2025
Researchers randomly assigned 7-8-week-old male C57BL/6 mice to a sham group or a 4.9 GHz RFR group (16 mice per group) and assessed anxiety, depression, cognition, sperm quality, and fertility in their male offspring. Paternal RFR exposure induced anxiety-like behaviors and impaired sperm quality in the first-generation male offspring. No significant effects were observed on depression-like behaviors, cognitive performance, or fertility across F1-F2 generations.
Unknown authors · 2025
Researchers collected data from 80 male workers in an automobile part manufacturing plant, including demographic characteristics, occupational exposures, biochemical markers, hormone levels, and sperm parameters. They trained five machine learning models using 5-fold cross-validation to predict reproductive health outcomes. Exposure to whole-body vibration, magnetic fields, electric fields, and heat stress closely affected free testosterone levels. The XGBoost and random forest models achieved the highest AUC of 0.99. Random Forest importance indicated electric field exposure (5%) and magnetic field exposure (4.7%) had the most substantial negative impact on free testosterone.
Unknown authors · 2025
The study and control groups were divided into four subgroups based on gestation week of exposure. Plasma estrogen and progesterone, primordial follicle counts, and nuclei diameters decreased significantly in exposed groups compared to sham. Primordial follicle apoptosis increased markedly in the study subgroups versus control and sham.
Vijay S et al. · 2025
Histological examination revealed vacuolation in the testes and corpus epididymis of both exposed groups and multifocal atypical hyperplasia in the seminal vesicle. Seminiferous tubule diameter decreased gradually in both exposed groups with a substantial decrease in the 24-hour group, and the spermatogenesis index was significantly reduced in both exposed groups. Sperm concentration was significantly reduced in both exposed groups, sperm motility decreased significantly in the 4-hour group, and sperm viability increased substantially in the 24-hour group.
Unknown authors · 2025
The study enrolled 1,666 women in the Yazd Mother and Child Cohort between 2015 and 2019 and examined exposure to cell phones, cordless phones, and Wi-Fi. Outcomes included miscarriage, preterm labor, abnormal birth weight, and deviations in newborn height and head circumference. Longer cell phone call duration was associated with higher risks of miscarriage, abnormal birth weight, and height, while cordless phone conversations could increase the risk of abnormal weight in newborns.
Pal S, Paladhi P, Dutta S, Ghosh P, Chattopadhyay R, Ghosh S · 2025
Researchers genotyped 708 azoospermic men and 640 healthy controls for variants in SPO11, RNF212, and SYCP3 using Sanger sequencing. Binary logistic regression assessed the interaction between genetic variants, electronic radiation exposure, and age on fertility status. The analysis found a significant association between these genetic variations and increased azoospermia risk, particularly in men aged 30 or older exposed to electronic radiation.
Unknown authors · 2025
Researchers conducted a cross-sectional observational study with 102 healthy males aged 20–35 years in an IVF laboratory. Semen samples were exposed to different EMF sources for one hour and motility was assessed immediately. Progressive sperm motility decreased significantly after exposure to mobile phone and Wi-Fi repeater EMFs, but other equipment had no significant effect.
Unknown authors · 2025
Researchers exposed adult zebrafish to 4 hours of RF-EMR daily from a 4G Wi-Fi router for 30 days. After exposure, the fish were bred on days 10, 20, and 30, and the resulting embryos were raised without EMF and examined up to 10 days post-fertilization. Histopathology showed testicular and ovarian abnormalities in exposed adults, while their offspring exhibited increased mortality, morphological malformations, and anxiety-like behavior at 10 days post-fertilization.
Syed Taha SMA et al. · 2025
Male Sprague Dawley rats (n = 6 per group) were exposed for 60 days to 3.5 GHz or 24 GHz RF-EMF for 1 h/day or 7 h/day, and testicular cytokines, apoptosis-related genes, and sperm quality were evaluated. IL-10 was significantly reduced in the 24 GHz group at both 1-h and 7-h exposure duration, and at 7 h TNF-α was also lower at 24 GHz. Casp3 expression was higher and Tp53 was lower at 3.5 GHz at 1-h exposure duration. Sperm concentration and viability were reduced after 24 GHz exposure at 7 h, while sperm motility was reduced after 3.5 GHz exposure at both durations.
Gelenli Dolanbay E et al. · 2025
Pregnant Wistar Hannover rats were divided into sham control, full-gestation exposure (3T RFR), and late-gestation exposure (2T RFR) groups with 2 hours of exposure per day. Male offspring were euthanized at 12 months for testicular analysis. In the full-gestation exposure group, seminiferous tubule diameter and epithelial height were significantly reduced compared to controls. Abnormal sperm morphology increased significantly in the full-gestation exposure group. DNA damage markers and apoptosis were elevated in both exposure groups compared to sham.
Unknown authors · 2025
The study applied continuous Wi-Fi radiation at 2.4 GHz and 200–500 µW/m² for nine days to chicken embryos. Overall mesonephros development was not adversely affected, but moderate diffuse degenerative changes appeared in mesonephric corpuscles and tubules. Congested blood vessels were observed in the interstitium without inflammatory infiltrate. The exposed group showed significantly more apoptotic and proliferating cells and up-regulated caspase-1 gene expression.
Yilmaz H, Tümkaya L, Mercantepe T, Yılmaz A, Gül F, Suzan ZT · 2025
Researchers exposed male Sprague-Dawley rats to 5.9 GHz electromagnetic fields for two hours daily over 30 days. The EMF exposure caused histopathological damage including edema, vascular congestion, inflammation, and loss of sperm cells. EMF exposure also increased oxidative stress markers and endoplasmic reticulum stress proteins in testicular tissue. Coenzyme Q10 treatment reversed both the histopathological and biochemical changes caused by EMF exposure.
Unknown authors · 2025
Researchers exposed female Wistar rats to 700MHz radiation for short-term (6 hours daily for 10 days) and long-term (4 hours daily for 60 days) periods. No changes were seen in estrous cycles or DNA damage in either exposure group. Testosterone levels increased significantly in exposed rats, while estradiol and progesterone remained normal. Exposed ovaries showed elevated malondialdehyde and reduced superoxide dismutase, total sulfhydryl content, and ferric reducing antioxidant power. Histopathology revealed no significant ovarian morphology changes after short-term exposure but cystic follicles and abnormal vasculature after long-term exposure.
Gautam R, Jha N, Tomar AK, Nirala JP, Arora T, Rajamani P · 2025
The exposed group received 35.5 GHz millimeter wave radiation for 2 hours per day over 60 days. Exposure significantly reduced sperm viability and count and caused morphometric changes in testicular tissue. Lipid peroxidation increased while superoxide dismutase, total sulfhydryl levels, and total antioxidant capacity decreased in exposed rats. DNA damage measured by comet assay was significantly increased in the exposed group.
Unknown authors · 2024
After four weeks the offspring were sacrificed and hippocampal, kidney, and liver tissues were examined for injury. EMF exposure increased necrotic areas in the hippocampus, hyperemia and necrosis in the kidneys, and degeneration in the liver compared with the group that received both EMF and curcumin. Daily curcumin during pregnancy prevented these tissue injuries in the fetuses.
Unknown authors · 2024
Researchers exposed mouse zygotes to cell phone electromagnetic radiation at 900-1800 MHz for 30 minutes on day 1. Exposed embryos showed slower cleavage divisions, more abnormal cleavage patterns, and delayed blastocyst formation. Cell survival in blastocysts was lower in the exposed group.
Mahmoudi R et al. · 2024
Researchers divided 32 adult male Wistar rats into four groups: control, RF-EMF alone, heat stress alone, and RF-EMF combined with heat stress. Rats in the RF-EMF group were exposed for 2 hours daily over 52 days, while the heat stress group received 10 minutes of heat per day for the same period. After 52 days, the combined RF-EMF and heat group showed significant improvements in testis volume, tubular epithelium, interstitium, cell counts, sperm quality, and Leydig cells compared with the heat-only group.
Unknown authors · 2024
Karamazı Y, Emre M, Uçar S, Aksoy G, Emre T, Tokuş M · 2024
The study used 20 female and 20 male Wistar Albino rats divided into four groups with different exposure patterns to 6 GHz RF-EMF at 0.054 W/kg. Rats were exposed for 4 hours per day for 6 weeks before mating, and pregnant rats in Group-II and Group-III were exposed for 4 hours per day for 18 days of gestation. Fetal weight, body lengths, and bone measurements all increased significantly in every exposure group compared with controls.
Unknown authors · 2024
The study aimed to determine the effect of electromagnetic waves from mobile phone stations on sperm parameters and the male reproductive system. Researchers enrolled 216 men aged 18 to 60 years, dividing them into two equal groups based on whether they lived close to cell phone tower stations for at least six months or 100 meters away. The exposed group showed a trend toward a lower percentage of normal sperm morphology compared to the non-exposed group, but the difference was not statistically significant. The exposed group also showed trends toward decreased total sperm motility and progressive sperm motility, again without statistical significance.
Unknown authors · 2024
Researchers conducted a retrospective study of 1495 pregnant women who gave birth at Konya City Hospital between September 2020 and February 2021. They recorded phone model, average daily phone time, and neonatal outcomes including birth weight, length, head circumference, APGAR scores, and delivery type. The rate of delivering a small-for-gestational-age baby was significantly higher in women who used phones with higher SAR values (p=0.001). A SAR cut-off of 1.23 W/kg showed 69.3% sensitivity and 73.0% specificity for predicting SGA birth. No correlation was found between daily phone use time and SGA birth rate.
Unknown authors · 2024
The study aimed to evaluate the protective effects of edible bird nest against the detrimental impact of Wi-Fi on male reproductive health. It examined whether edible bird nest can mitigate Wi-Fi-induced changes in male reproductive hormones, estrogen receptors, spermatogenesis, and sperm parameters.