3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
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Brain & Nervous System

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Key Finding: 78% of 1,644 studies on brain & nervous system found biological effects from EMF exposure.

Of 1,644 studies examining brain & nervous system, 78% found measurable biological effects from EMF exposure.

Lowest Documented Effect

Research found effects on brain & nervous system at exposures as low as:

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in Context0.0000000043Extreme Concern5 mGFCC Limit2,000 mGEffects observed in the No Concern range (Building Biology)FCC limit is 465,116,279,070x higher than this exposure level

Research Overview

  • -When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research.
  • -Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
  • -This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health. This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

Henry Lai's comprehensive analysis of peer-reviewed research, 91% of studies examining extremely low frequency fields found biological effects on the nervous system, while 72% of radiofrequency studies showed similar impacts.

The scientific evidence demonstrates that radiofrequency electromagnetic fields from mobile phones and wireless devices produce measurable effects on nervous system function and cellular processes in the brain.

Source: BioInitiative Working Group. BioInitiative Report: A Rationale for Biologically-based Public Exposure Standards for Electromagnetic Radiation. Edited by Cindy Sage and David O. Carpenter, BioInitiative, 2012, updated 2020. www.bioinitiative.org

Research Statistics by EMF Type

EMF TypeStudiesShowing EffectsPercentage
ELF22920891.00%
RF30522272.00%

Source: Dr. Henry Lai research database, BioInitiative Report

Showing 1,644 studies

Transduction of the Geomagnetic Field as Evidenced from alpha-Band Activity in the Human Brain.

Wang CX et al. · 2019

Researchers exposed participants to Earth-strength magnetic fields while monitoring their brain activity with EEG. They discovered that specific magnetic field rotations caused measurable changes in brain waves (alpha oscillations), but only when the field was oriented as it naturally occurs in the Northern Hemisphere. This suggests humans possess an unconscious magnetic sensing ability similar to migratory animals.

Correlation between the Lunar Phase and Tail-Lifting Behavior of Lizards (Pogona vitticeps) Exposed to an Extremely Low-Frequency Electromagnetic Field.

Nishimura T, Tada H, Fukushima M. · 2019

Researchers exposed bearded dragon lizards to extremely low-frequency electromagnetic fields (ELF-EMF) and found that exposed lizards became more sensitive to natural magnetic field changes, including lunar phases. The EMF-exposed lizards showed increased tail-lifting behavior during full moons, while unexposed control lizards showed no such response. This suggests that artificial EMF exposure may enhance animals' natural magnetic field sensitivity.

The Effects of Mobile Phone Radiofrequency Electromagnetic Fields on β-Amyloid-Induced Oxidative Stress in Human and Rat Primary Astrocytes.

Tsoy A et al. · 2019

Researchers exposed brain cells called astrocytes to 918 MHz radiofrequency radiation (similar to cell phone signals) along with proteins that cause Alzheimer's disease damage. Surprisingly, they found that the RF exposure actually reduced harmful oxidative stress and protected the cells from damage caused by the Alzheimer's proteins. The study suggests that certain RF frequencies might have therapeutic potential for treating Alzheimer's disease.

Effects of single- and hybrid-frequency extremely low-frequency electromagnetic field stimulations on long-term potentiation in the hippocampal Schaffer collateral pathway.

Zheng Y, Ma XX, Dong L, Gao Y, Tian L. · 2019

Researchers exposed rat brain tissue to 15 Hz magnetic fields at medical device levels to study effects on brain connections. The magnetic fields significantly disrupted normal brain signaling that supports learning and memory, showing common electromagnetic frequencies can interfere with basic brain functions.

Effects of 5-HT1 and 5-HT 2 Receptor Agonists on Electromagnetic Field-Induced Analgesia in Rats.

Ozdemir E, Demirkazik A, Taskıran AS, Arslan G. · 2019

Researchers exposed rats to 50 Hz magnetic fields (the same frequency as power lines) for 2 hours daily over 15 days and found the fields produced pain relief (analgesia). They discovered this pain-blocking effect works through serotonin receptors in the brain - the same chemical system involved in mood and sleep. The study shows that extremely low frequency magnetic fields can directly alter brain chemistry and pain perception.

Effects of pulsed electromagnetic fields on learning and memory abilities of STZ-induced dementia rats.

Li Y, Zhang Y, Wang W, Zhang Y, Yu Y, Cheing GL, Pan W. · 2019

Researchers exposed rats with chemically-induced dementia to pulsed magnetic fields (10 mT at 20 Hz) and found dramatic improvements in learning and memory abilities. The treated rats showed 66% faster escape times in maze tests and 55% shorter swimming distances compared to untreated dementia rats. The magnetic field exposure also increased expression of genes linked to brain growth and repair, suggesting the fields may help protect against cognitive decline.

A comparative study on influences of static electric field and power frequency electric field on cognition in mice.

Di G, Kim H, Xu Y, Kim J, Gu X. · 2019

Researchers exposed mice to extremely strong electric fields (35,000 volts per meter) for 49 days to compare how static fields versus power frequency fields affect learning and memory. They found that static electric fields had no effect on cognitive ability, while power frequency electric fields actually improved the mice's performance on memory tests after 33 days of exposure.

Effect of 900-, 1800-, and 2100-MHz radiofrequency radiation on DNA and oxidative stress in brain

Alkis ME et al. · 2019

Turkish researchers exposed rats to cell phone radiation at three different frequencies (900, 1800, and 2100 MHz) for 2 hours daily over 6 months to study brain effects. They found increased DNA damage and oxidative stress in brain tissue across all frequency groups compared to unexposed control rats. This suggests that chronic exposure to the radiofrequency radiation emitted by mobile phones may harm brain cells at the genetic level.

Effects of exposure to extremely low-frequency electromagnetic fields on spatial and passive avoidance learning and memory, anxiety-like behavior and oxidative stress in male rats.

Karimi SA, Salehi I, Shykhi T, Zare S, Komaki A. · 2019

Researchers exposed male rats to extremely low-frequency electromagnetic fields (ELF-EMF) for 2 hours daily over 60 days at various intensities. They found that certain exposure levels improved memory retention and passive learning, but also increased anxiety-like behaviors and oxidative stress (cellular damage from unstable molecules). This suggests ELF-EMF exposure creates a complex mix of both beneficial and harmful effects on brain function.

Brain & Nervous SystemNo Effects Found

Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice.

Jeong YJ et al. · 2018

Researchers exposed middle-aged mice to cell phone-level radiofrequency radiation (1950 MHz) for 8 months to see if it worsened age-related brain damage. While the aging mice showed expected increases in brain oxidative stress, DNA damage, and inflammation markers, the RF exposure didn't make any of these problems worse. The study suggests that long-term exposure to this type of radiation may not accelerate brain aging processes.

Brain & Nervous SystemNo Effects Found

50-Hz magnetic field impairs the expression of iron-related genes in the in vitro SOD1G93A model of amyotrophic lateral sclerosis.

Consales C et al. · 2018

Researchers exposed lab-grown nerve cells with ALS-related genetic mutations to 50 Hz magnetic fields (the same frequency as power lines) for up to 72 hours. They found that while the magnetic field didn't kill cells or increase oxidative stress, it disrupted iron metabolism genes specifically in cells with the SOD1G93A mutation linked to familial ALS. This suggests that power frequency magnetic fields may interfere with cellular iron regulation in genetically susceptible individuals.

Association between mobile phone use and depressed mood in Japanese adolescents: a cross-sectional study.

Ikeda K, Nakamura K. · 2018

Researchers studied nearly 2,800 Japanese high school students to see if heavy mobile phone use was linked to mood problems. Students using phones more than 33 hours per week showed significantly higher levels of depression, tension, and fatigue compared to lighter users. This suggests that excessive phone use may negatively impact teenagers' mental health.

Transcranial static magnetic field stimulation (tSMS) of the visual cortex decreases experimental photophobia.

Lozano-Soto E et al. · 2018

Researchers tested whether placing a static magnet on the back of the head could reduce light sensitivity (photophobia) in 20 healthy volunteers. They found that 10 minutes of magnetic field exposure significantly reduced discomfort from bright lights compared to a fake treatment. This suggests the visual cortex in the brain contributes to light sensitivity and that magnetic field therapy might help treat photophobia in migraine patients.

Transcranial Static Magnetic Field Stimulation over the Primary Motor Cortex Induces Plastic Changes in Cortical Nociceptive Processing.

Kirimoto H et al. · 2018

Researchers applied static magnetic fields to the brain's motor cortex for 15 minutes and found it reduced how strongly participants responded to painful electrical stimuli. The magnetic stimulation appeared to change how the brain processes pain signals, with effects lasting at least 10 minutes after the treatment ended. This suggests static magnetic fields might potentially be developed as a non-invasive treatment for chronic pain conditions.

Decrease of motor cortex excitability following exposure to a 20 Hz magnetic field as generated by a rotating permanent magnet.

Gallasch E, Rafolt D, Postruznik M, Fresnoza S, Christova M. · 2018

Researchers exposed 14 healthy volunteers to 20 Hz magnetic fields generated by rotating permanent magnets for 15 minutes, then measured brain activity in the motor cortex (the brain region controlling movement). They found that this magnetic field exposure significantly reduced motor cortex excitability, meaning the brain region became less responsive to stimulation. This demonstrates that even brief exposure to rotating magnetic fields can measurably alter brain function.

Low Frequency Stimulation Reverses the Kindling-Induced Impairment of Learning and Memory in the Rat Passive-avoidance Test.

Esmaeilpour K et al. · 2018

Researchers studied whether low-frequency electrical stimulation (1 Hz) could help reverse memory problems caused by seizures in rats. They found that applying brief electrical stimulation treatments after seizures not only restored learning and memory abilities but also protected brain cells from seizure-related damage. This suggests that controlled electrical stimulation might offer a therapeutic approach for treating cognitive problems in epilepsy patients.

Long-lasting effects of transcranial static magnetic field stimulation on motor cortex excitability.

Dileone M, Mordillo-Mateos L, Oliviero A, Foffani G. · 2018

Researchers applied static magnetic fields to the motor cortex of 45 healthy volunteers for 30 minutes and measured brain activity changes using magnetic stimulation tests. They found that longer magnetic field exposure (30 minutes) created lasting changes in brain excitability that persisted for at least 30 minutes after exposure ended, while shorter exposure (10 minutes) produced only temporary effects. This suggests that magnetic field duration matters significantly for how our brains respond to electromagnetic stimulation.

Extremely low frequency electromagnetic field reduces oxidative stress during the rehabilitation of post-acute stroke patients.

Cichoń N, Rzeźnicka P, Bijak M, Miller E, Miller S, Saluk J. · 2018

Researchers studied 57 stroke patients who received either standard physical therapy alone or combined with extremely low frequency electromagnetic field (ELF-EMF) therapy. Patients receiving the electromagnetic field treatment showed significantly reduced oxidative stress markers in their blood and better improvements in daily activities, mental function, and depression scores compared to those getting standard therapy alone. This suggests that ELF-EMF therapy may enhance stroke rehabilitation by reducing cellular damage and improving recovery outcomes.

Modulation of antioxidant enzyme gene expression by extremely low frequency electromagnetic field in post-stroke patients.

Cichon N et al. · 2018

Researchers studied 48 stroke patients who received either standard physical therapy alone or physical therapy plus extremely low frequency electromagnetic field (ELF-EMF) treatment. They found that patients receiving ELF-EMF therapy showed significantly increased activity in genes that produce antioxidant enzymes - the body's natural defense system against cellular damage. This suggests ELF-EMF therapy may help stroke patients recover by boosting their cells' ability to protect themselves from harmful oxidative stress.

Increase in Blood Levels of Growth Factors Involved in the Neuroplasticity Process by Using an Extremely Low Frequency Electromagnetic Field in Post-stroke Patients.

Cichoń N et al. · 2018

Polish researchers studied whether extremely low frequency electromagnetic fields could help stroke patients recover brain function during rehabilitation. They found that patients receiving EMF therapy alongside standard rehabilitation showed significantly higher levels of brain growth factors that promote healing and scored better on cognitive and functional recovery tests. This suggests EMF therapy may enhance the brain's natural ability to rewire itself after stroke damage.

POSSIBLE IMPLEMENTATION OF GABAERGIC AND GLUTAMATERGIC SYSTEMS IN REALIZATION OF ANTIEPILEPTIC EFFECTS OF ACOUSTIC RANGE ELECTRO - MAGNETIC FIELDS.

Bukia N et al. · 2018

Researchers studied whether low-frequency electromagnetic fields could reduce seizures in epileptic rats by affecting brain chemical systems. They found that acoustic-range electromagnetic exposure decreased seizure activity by changing how neurotransmitters (brain chemicals like GABA and glutamate) function in the brain. This suggests electromagnetic fields might influence seizure disorders through specific brain chemistry pathways.

A histopathological and biochemical evaluation of oxidative injury in the sciatic nerves of male rats exposed to a continuous 900-megahertz electromagnetic field throughout all periods of adolescence.

Kerimoğlu G, Güney C, Ersöz Ş, Odacı E. · 2018

Turkish researchers exposed adolescent male rats to 900 MHz electromagnetic fields (the frequency used by many cell phones) for one hour daily throughout their entire teenage development period. They found significant nerve damage in the sciatic nerve, including structural changes and increased oxidative stress markers that indicate cellular damage. This suggests that regular EMF exposure during critical developmental periods may harm the peripheral nervous system.

Long term exposure to cell phone frequencies (900 and 1800 MHz) induces apoptosis, mitochondrial oxidative stress and TRPV1 channel activation in the hippocampus and dorsal root ganglion of rats.

Ertilav K, Uslusoy F, Ataizi S, Nazıroğlu M. · 2018

Researchers exposed rats to cell phone frequencies (900 and 1800 MHz) for one hour daily, five days a week for an entire year, then examined brain tissue for damage. They found significant cellular damage including cell death, oxidative stress, and disrupted calcium channels in the hippocampus (memory center) and nerve tissues. The higher frequency (1800 MHz) caused more severe damage than the lower frequency, suggesting a dose-response relationship.

Effect of low-level 1800 MHz radiofrequency radiation on the rat sciatic nerve and the protective role of paricalcitol.

Comelekoglu U et al. · 2018

Turkish researchers exposed rats to 1800 MHz radiofrequency radiation (the same frequency used by many cell phones) for one hour daily over four weeks and found significant damage to the sciatic nerve, which controls leg function. The nerve damage included slower electrical signals, increased oxidative stress, and physical deterioration of nerve fibers. However, when rats were also given paricalcitol (a vitamin D derivative), the nerve damage was partially prevented.

Learn More

For a comprehensive exploration of EMF health effects including brain & nervous system, along with practical protection strategies, explore these books by R Blank and Dr. Martin Blank.

FAQs: EMF & Brain & Nervous System

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
The BioInitiative Report database includes 1,644 peer-reviewed studies examining the relationship between electromagnetic field exposure and brain & nervous system. These studies have been conducted by researchers worldwide and published in scientific journals. The research spans multiple decades and includes various types of EMF sources including cell phones, WiFi, power lines, and other common sources of electromagnetic radiation.
78% of the 1,644 studies examining brain & nervous system found measurable biological effects from EMF exposure. This means that 1284 studies documented observable changes in biological systems when exposed to electromagnetic fields. The remaining 22% either found no significant effects or had inconclusive results, which is typical in scientific research where study design and exposure parameters vary.