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Measurement of the 100 MHz EMF radiation in vivo effects on zebrafish D. rerio embryonic development: A multidisciplinary study.

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Piccinetti CC, De Leo A, Cosoli G, Scalise L, Randazzo B, Cerri G, Olivotto I. · 2018

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The study found that 100 MHz EMF exposure affected zebrafish embryonic development from 24 to 72 hours post-fertilization.

Plain English Summary

Summary written for general audiences

Researchers evaluated the biological effects of 100 MHz radiofrequency electromagnetic field exposure on zebrafish embryos using a multidisciplinary protocol. The 100 MHz EMF affected zebrafish embryonic development from 24 to 72 hours post-fertilization across all analyzed pathways. At 48 hours post-fertilization, reduced growth, increased oxidative stress gene transcription, apoptotic and autophagic processes, and modified cholesterol metabolism were detected. By 72 hours post-fertilization, embryos partially recovered from stress and reached hatching time comparable to controls.

Why This Matters

The data demonstrated in vivo effects of RF-EMF on an animal model while excluding thermal outcomes. Zebrafish were selected as the experimental model due to shared synteny between human and zebrafish genomes. A measurement protocol and biological analyses were established to discriminate between RF-EMF biological and thermal effects.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 100 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 100 MHzPower lines50/60 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 100 MHz

Study Details

The present study aims to evaluate the biological effects on zebrafish (ZF) embryos of 100 MHz radiofrequency electromagnetic field (RF-EMF) exposure through a multidisciplinary protocol.

Because of the shared synteny between human and ZF genomes that validated its use in biomedical rese...

The results showed that a 100 MHz EMF was able to affect ZF embryonic development, from 24 to 72 h p...

Data here obtained showed unequivocally the in vivo effects of RF-EMF on an animal model, excluding thermal outcomes and thus represents the starting point for more comprehensive studies on dose response effects of electromagnetic fields radiations consequences.

Cite This Study
Piccinetti CC, De Leo A, Cosoli G, Scalise L, Randazzo B, Cerri G, Olivotto I. (2018). Measurement of the 100 MHz EMF radiation in vivo effects on zebrafish D. rerio embryonic development: A multidisciplinary study. Ecotoxicol Environ Saf. 154:268-279, 2018.
Show BibTeX
@article{cc_2018_measurement_of_the_100_1698,
  author = {Piccinetti CC and De Leo A and Cosoli G and Scalise L and Randazzo B and Cerri G and Olivotto I.},
  title = {Measurement of the 100 MHz EMF radiation in vivo effects on zebrafish D. rerio embryonic development: A multidisciplinary study.},
  year = {2018},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0147651318301489},
}

Quick Questions About This Study

The study exposed zebrafish embryos to 100 MHz radiofrequency electromagnetic fields.
At 48 hours post-fertilization, reduced growth, increased oxidative stress gene transcription, apoptotic and autophagic processes, and modified cholesterol metabolism were detected.
By 72 hours post-fertilization, embryos partially recovered from stress and reached hatching time comparable to controls.
Zebrafish were selected due to shared synteny between human and zebrafish genomes that validates their use in biomedical research.
The study excluded thermal outcomes and established a protocol to discriminate between biological and thermal effects.