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Brain & Nervous System

Transcranial magnetic stimulation attenuates cell loss and oxidative damage in the striatum induced in the 3-nitropropionic model of Huntington's disease.

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Túnez I, Drucker-Colín R, Jimena I, Medina FJ, Muñoz Mdel C, Peña J, Montilla P · 2006

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Controlled magnetic stimulation protected brain cells from damage in this study, showing therapeutic potential for neurodegenerative diseases.

Plain English Summary

Summary written for general audiences

Researchers tested whether transcranial magnetic stimulation (TMS) could protect brain cells from damage caused by a toxic chemical that mimics Huntington's disease in rats. They found that TMS prevented cell death and reduced harmful oxidative stress in the brain region most affected by the disease. This suggests magnetic field therapy might offer neuroprotective benefits for degenerative brain conditions.

Study Details

An investigation was conducted on the effect of transcranial magnetic field stimulation (TMS) on the free radical production and neuronal cell loss produced by 3-nitropropionic acid in rats.

The effects of 3-nitropropionic acid were evaluated by examining the following changes in: the quant...

Our results reveal that 3-nitropropionic acid induces oxidative and nitrosative stress in the striat...

In conclusion, the results show the ability of TMS to modify neuronal response to 3-nitropropionic acid.

Cite This Study
Túnez I, Drucker-Colín R, Jimena I, Medina FJ, Muñoz Mdel C, Peña J, Montilla P (2006). Transcranial magnetic stimulation attenuates cell loss and oxidative damage in the striatum induced in the 3-nitropropionic model of Huntington's disease. J Neurochem. 97(3):619-630, 2006.
Show BibTeX
@article{i_2006_transcranial_magnetic_stimulation_attenuates_2858,
  author = {Túnez I and Drucker-Colín R and Jimena I and Medina FJ and Muñoz Mdel C and Peña J and Montilla P},
  title = {Transcranial magnetic stimulation attenuates cell loss and oxidative damage in the striatum induced in the 3-nitropropionic model of Huntington's disease.},
  year = {2006},
  doi = {10.1111/j.1471-4159.2006.03724.x},
  url = {https://onlinelibrary.wiley.com/doi/full/10.1111/j.1471-4159.2006.03724.x},
}
DOI: 10.1111/j.1471-4159.2006.03724.x

Cited By (60 papers)

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Quick Questions About This Study

Research shows transcranial magnetic stimulation (TMS) can protect brain cells from damage. A 2006 study found TMS prevented cell death and reduced harmful oxidative stress in rats with chemically-induced brain damage similar to Huntington's disease, suggesting potential neuroprotective benefits.
TMS appears to have protective effects on brain tissue rather than harmful ones. The 2006 study by Túnez and colleagues found that magnetic stimulation actually prevented brain cell loss and oxidative damage, indicating safety and potential therapeutic benefits for neurodegenerative conditions.
Early research suggests magnetic field therapy might help protect against brain damage in Huntington's disease. A 2006 animal study found transcranial magnetic stimulation prevented cell death and oxidative stress in brain regions affected by this degenerative condition.
TMS appears to prevent brain cell death by reducing oxidative stress. Research using a Huntington's disease model found that transcranial magnetic stimulation protected neurons from toxic damage and prevented the cell loss typically caused by neurodegenerative processes.
Magnetic brain stimulation may offer neuroprotective benefits by preventing cell damage and death. A 2006 study found TMS reduced oxidative stress and protected brain cells from toxic injury, suggesting potential therapeutic applications for neurodegenerative diseases like Huntington's.