Influence of extremely-low-frequency magnetic field on antioxidative melatonin properties in AT478 murine squamous cell carcinoma culture.
Zwirska-Korczala K, Adamczyk-Sowa M, Polaniak R, Sowa P, Birkner E, Drzazga Z, Brzozowski T, Konturek SJ · 2004
View Original AbstractELF magnetic fields significantly weakened melatonin's antioxidant protection in cells, suggesting everyday EMF exposure may compromise natural cellular defenses.
Plain English Summary
Researchers studied how extremely-low-frequency magnetic fields (ELF-MF) affect melatonin's protective properties in cancer cells. They found that while melatonin alone boosted the cells' antioxidant defenses, exposure to ELF-MF significantly weakened these protective effects. This suggests that magnetic field exposure may interfere with the body's natural defense mechanisms against cellular damage.
Why This Matters
This research reveals a concerning interaction between magnetic field exposure and one of our body's most important protective hormones. Melatonin serves as a powerful antioxidant that helps cells defend against damage, but this study demonstrates that ELF-MF exposure can significantly diminish these protective effects. What makes this particularly relevant is that ELF magnetic fields are generated by power lines, electrical wiring, and common household appliances. The science demonstrates that even our natural cellular defenses may be compromised by everyday EMF exposure. While this study used cancer cells in laboratory conditions, the implications extend to understanding how magnetic fields might affect healthy cellular function throughout the body.
Exposure Information
Specific exposure levels were not quantified in this study.
Study Details
Effects of melatonin, extremely-low-frequency magnetic field (ELF-MF), and their combination on AT478 murine squamous cell carcinoma line were studied.
Manganese superoxide dismutase (MnSOD), copper-zinc superoxide dismutase (Cu/ZnSOD), and glutathione...
After melatonin treatment, antioxidative enzyme activities were increased and MDA level was decrease...
These results strongly suggest that ELF-MF attenuates antioxidative actions of melatonin on cellular level
Show BibTeX
@article{k_2004_influence_of_extremelylowfrequency_magnetic_1607,
author = {Zwirska-Korczala K and Adamczyk-Sowa M and Polaniak R and Sowa P and Birkner E and Drzazga Z and Brzozowski T and Konturek SJ},
title = {Influence of extremely-low-frequency magnetic field on antioxidative melatonin properties in AT478 murine squamous cell carcinoma culture.},
year = {2004},
doi = {10.1385/BTER:102:1-3:227},
url = {https://link.springer.com/article/10.1385/BTER:102:1-3:227},
}