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DNA & Genetic Damage

Measurement of DNA damage in mammalian cells exposed in vitro to radiofrequency fields at sars of 3-5 w/kg.

No Effects Found

Li L, Bisht KS, LaGroye I, Zhang P, Straube WL, Moros EG, Roti Roti JL. · 2001

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This study found no DNA damage from 24-hour RF exposure at cell phone-level intensities, but doesn't address long-term cumulative effects.

Plain English Summary

Summary written for general audiences

Researchers exposed mouse cells to radiofrequency radiation at levels of 3.2-5.1 watts per kilogram (similar to cell phone exposure levels) for up to 24 hours to see if it would damage DNA. Using a sensitive test called the comet assay, they found no detectable DNA damage in the exposed cells compared to unexposed control cells. This suggests that RF exposure at these specific levels and durations may not cause immediate genetic damage in laboratory conditions.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 847.7 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 847.7 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 847.74 MHz (CDMA) and 835.62 (FDMA) Duration: 2, 4 or 24 h

Study Details

In the present study, we determined whether exposure of mammalian cells to 3.2-5.1 W/kg specific absorption rate (SAR) radiofrequency fields could induce DNA damage in murine C3H 10T(1/2) fibroblasts.

Cell cultures were exposed to 847.74 MHz code-division multiple access (CDMA) and 835.62 frequency-d...

Using the alkaline comet assay to measure DNA damage, we found no statistically significant differen...

Our results show that exposure of cultured C3H 10T(1/2) cells at 37 degrees C CDMA or FDMA at SAR values of up to 5.1 W/kg did not induce measurable DNA damage.

Cite This Study
Li L, Bisht KS, LaGroye I, Zhang P, Straube WL, Moros EG, Roti Roti JL. (2001). Measurement of DNA damage in mammalian cells exposed in vitro to radiofrequency fields at sars of 3-5 w/kg. Radiat Res 156:328-332, 2001.
Show BibTeX
@article{l_2001_measurement_of_dna_damage_2918,
  author = {Li L and Bisht KS and LaGroye I and Zhang P and Straube WL and Moros EG and Roti Roti JL.},
  title = {Measurement of DNA damage in mammalian cells exposed in vitro to radiofrequency fields at sars of 3-5 w/kg.},
  year = {2001},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/11500143/},
}
PubMed: 11500143

Cited By (61 papers)

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Quick Questions About This Study

No, a 2001 study found that mouse cells exposed to 847 MHz CDMA radiation at 3.2-5.1 watts per kilogram for up to 24 hours showed no detectable DNA damage. Researchers used the sensitive comet assay to measure genetic damage and found no significant differences between exposed and control cells.
Research shows that 835 MHz FDMA radiation at cell phone-like exposure levels (up to 5.1 W/kg) does not cause measurable DNA damage in cultured mouse cells. Even after 24-hour exposures, scientists detected no significant genetic damage using precise laboratory testing methods.
Laboratory studies demonstrate that mouse cells can be exposed to radiofrequency radiation at 5.1 watts per kilogram for up to 24 hours without detectable DNA damage. Testing at 2, 4, and 24-hour intervals all showed no significant genetic effects compared to unexposed cells.
The alkaline comet assay, a sensitive test for DNA damage, found no genetic harm when mouse cells were exposed to cell phone frequencies (835-847 MHz) at typical exposure levels. This laboratory method can detect subtle DNA changes but showed no effects from radiofrequency radiation.
No, C3H 10T1/2 mouse cells showed no DNA damage when exposed to both CDMA (847 MHz) and FDMA (835 MHz) radiation at levels up to 5.1 W/kg. Researchers tested both actively growing and resting cells with identical negative results for genetic damage.