Adaptive Response Induced by Pre-Exposure to 915 MHz Radiofrequency: A Possible Role for Antioxidant Enzyme Activity.
Mortazavi SMJ, Mostafavi-Pour Z, Daneshmand M, Zal F, Zare R, Mosleh-Shirazi MA. · 2017
View Original AbstractPre-exposure to 915 MHz radiofrequency radiation induced adaptive response in liver by increasing glutathione levels and glutathione reductase activity, which protected tissue from oxidative damage caused by gamma radiation.
Plain English Summary
Researchers divided 50 rats into five groups and pre-exposed three groups to 915 MHz radiofrequency radiation for 4 hours daily over one week at low, medium, and high power. Twenty-four hours after the last exposure, the rats were given a 4 Gy sublethal gamma radiation dose and sacrificed after 5 hours. Pre-exposure increased glutathione levels and glutathione reductase activity in liver, with glutathione increases only in the low power group and glutathione reductase activity increases in both low and medium power groups. The elevated antioxidant levels protected liver tissue from oxidative damage induced by the gamma radiation.
Why This Matters
The study aimed to determine if radiofrequency radiation could induce an adaptive response by altering antioxidant balance. Researchers measured glutathione levels and glutathione reductase activity in liver tissue to evaluate this adaptive response. The results indicated that pre-exposure to 915 MHz radiation at specific powers could induce adaptive response in liver by changing antioxidant enzyme activity and levels.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 915 MHz Duration: 4 hours per day for one week at different powers, as low, medium and high
Study Details
This study aimed to assess whether radiofrequency radiation can induce adaptive response by changing the antioxidant balance
In order to assess RF-induced adaptive response in tissues, we evaluated the level of GSH and the ac...
Our finding showed that pre-exposure to 915 MHz radiofrequency radiation with specific power could i...
It can be concluded that pre-exposure to microwave radiation could increase the level of GSH and the activity of GR enzyme, although these increases were seen just in low power group, and the GR activity was indicated in medium power group. This increase protects tissue from oxidative damage induced by sublethal dose of gamma radiation.
Show BibTeX
@article{smj_2017_adaptive_response_induced_by_1676,
author = {Mortazavi SMJ and Mostafavi-Pour Z and Daneshmand M and Zal F and Zare R and Mosleh-Shirazi MA.},
title = {Adaptive Response Induced by Pre-Exposure to 915 MHz Radiofrequency: A Possible Role for Antioxidant Enzyme Activity.},
year = {2017},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447250/},
}