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Gene expression and reproductive abilities of male Drosophila melanogaster subjected to ELF-EMF exposure.

Bioeffects Seen

Li SS, Zhang ZY, Yang CJ, Lian HY, Cai P · 2013

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EMF exposure altered expression of over 1,700 genes in fruit flies and reduced male reproductive ability, revealing widespread cellular disruption.

Plain English Summary

Summary written for general audiences

Researchers exposed fruit flies (Drosophila) to extremely low frequency electromagnetic fields and found significant changes in gene expression affecting reproduction, aging, and cellular stress responses. Short-term exposure reduced male reproductive ability and altered expression of over 1,300 genes, while long-term exposure changed expression of more than 1,700 genes. The study suggests EMF exposure may accelerate cellular aging and compromise reproductive function through effects on sperm development.

Why This Matters

This study adds to the growing body of evidence that EMF exposure creates biological effects at the cellular level, even when researchers don't specify exact exposure parameters. The finding that over 1,700 genes changed expression during long-term exposure demonstrates the widespread cellular disruption that EMFs can cause. What makes this research particularly significant is that it shows reproductive effects from short-term exposure - suggesting that even brief EMF encounters may impact fertility. The researchers identified specific pathways involved in sperm development, aging, and stress response that were disrupted by EMF exposure. While fruit flies aren't humans, they share fundamental cellular processes with us, and this type of gene expression analysis provides valuable insights into potential mechanisms of EMF harm that warrant serious attention in human health research.

Exposure Information

Specific exposure levels were not quantified in this study.

Study Details

The in vivo effects of short-term and long-term ELF–EMF exposure on male Drosophila melanogaster were studied using transcriptomic analysis for preliminary screening and QRT-PCR for further verification.

Transcriptomic analysis indicated that 439 genes were up-regulated and 874 genes were down-regulated...

This study demonstrates the bioeffects of ELF–EMF exposure and provides evidence for understanding the in vivo mechanisms of ELF–EMF exposure on male D. melanogaster.

Cite This Study
Li SS, Zhang ZY, Yang CJ, Lian HY, Cai P (2013). Gene expression and reproductive abilities of male Drosophila melanogaster subjected to ELF-EMF exposure. Mutat Res. 758(1-2):95-103, 2013.
Show BibTeX
@article{ss_2013_gene_expression_and_reproductive_1595,
  author = {Li SS and Zhang ZY and Yang CJ and Lian HY and Cai P},
  title = {Gene expression and reproductive abilities of male Drosophila melanogaster subjected to ELF-EMF exposure.},
  year = {2013},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S1383571813003008},
}

Quick Questions About This Study

Researchers exposed fruit flies (Drosophila) to extremely low frequency electromagnetic fields and found significant changes in gene expression affecting reproduction, aging, and cellular stress responses. Short-term exposure reduced male reproductive ability and altered expression of over 1,300 genes, while long-term exposure changed expression of more than 1,700 genes. The study suggests EMF exposure may accelerate cellular aging and compromise reproductive function through effects on sperm development.