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Transient and steady-state magnetic fields induce increased fluorodeoxyglucose uptake in the rat hindbrain.

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Frilot C 2nd, Carrubba S, Marino AA. · 2011

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Magnetic fields at power line levels trigger measurable brain activity changes in specific regions that control vital body functions.

Plain English Summary

Summary written for general audiences

Researchers exposed rats to magnetic fields from power lines and measured brain activity using glucose uptake imaging. The magnetic fields increased brain activity in the hindbrain region, but only at specific angles, suggesting brains contain specialized detectors that respond to magnetic field exposure.

Why This Matters

This study provides compelling evidence that the brain actively responds to magnetic field exposure at levels we encounter from power lines and electrical appliances. The 2.5 Gauss exposure used here is roughly 25 times stronger than typical household magnetic fields (which range from 0.1 to 1 Gauss), but well within levels found near power lines or electrical panels. What makes this research particularly significant is its use of PET imaging to directly visualize brain changes, moving beyond behavioral observations to show actual metabolic responses. The finding that field direction matters suggests our brains have evolved sophisticated mechanisms for detecting magnetic fields, challenging the assumption that low-level EMF exposure is biologically inert. The hindbrain location is especially noteworthy since this region controls vital functions like breathing and heart rate.

Exposure Details

Magnetic Field
25 mG
Source/Device
2.5‐G, 60‐Hz
Exposure Duration
45 min

Exposure Context

This study used 25 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 25 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the Extreme Concern range (Building Biology)FCC limit is 80x higher than this exposure level

Study Details

The authors wanted to extend results from previous studies and to study whether electromagnetic field transduction was dependent on the direction of the field, and whether the previously reported electromagnetic field effects on fluorodeoxyglucose (FDG) uptake (see Frilot 2nd et al. 2009) actually were related to those field effects.

Rats were exposed to a 2.5‐G, 60‐Hz magnetic field and the neuroanatomical region of glucose activat...

Increased glucose utilization occurred in hindbrain voxels when the field was applied orthogonally to the sagittal plane, but not when the angle between the field and the sagittal plane varied randomly. Distinct FDG activation effects were observed in response to transient (both onset and offset) and steady‐state magnetic stimuli. Observations of increased glucose utilization induced by magnetic stimuli and its dependence on the direction of the field suggested that signal transduction was mediated by a force detector and that the process and/or early posttransduction processing occurred in the hindbrain.

Cite This Study
Frilot C 2nd, Carrubba S, Marino AA. (2011). Transient and steady-state magnetic fields induce increased fluorodeoxyglucose uptake in the rat hindbrain. Synapse. 65(7):617-623, 2011.
Show BibTeX
@article{2nd_2011_transient_and_steadystate_magnetic_250,
  author = {Frilot C 2nd and Carrubba S and Marino AA.},
  title = {Transient and steady-state magnetic fields induce increased fluorodeoxyglucose uptake in the rat hindbrain.},
  year = {2011},
  doi = {10.1002/syn.20882},
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/syn.20882},
}

Quick Questions About This Study

Researchers exposed rats to magnetic fields from power lines and measured brain activity using glucose uptake imaging. The magnetic fields increased brain activity in the hindbrain region, but only at specific angles, suggesting brains contain specialized detectors that respond to magnetic field exposure.