50 Hz extremely low frequency electromagnetic fields enhance protein carbonyl groups content in cancer cells: effects on proteasomal systems
Authors not listed · 2009
Caco 2 cells exposed to 50 Hz, 1 mT electromagnetic fields for 24–72 hours showed a time-dependent increase in protein oxidation and global activation of the 20S proteasome.
Plain English Summary
Researchers exposed Caco 2 cells to 50 Hz, 1 mT electromagnetic fields for 24–72 hours to study protein oxidation and 20S proteasome functionality. The exposure caused a time-dependent increase in cell growth and protein oxidation, more pronounced with TPA, but did not affect cell viability. The fields also globally activated the 20S proteasome catalytic components, especially at 72 hours and with TPA, and the antioxidant EGCG reversed these pro-oxidant effects, indicating the activation was due to increased free radicals.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{50_hz_extremely_low_frequency_electromagnetic_fields_enhance_protein_carbonyl_groups_content_in_cancer_cells_effects_on_proteasomal_systems_ce1389,
author = {Unknown},
title = {50 Hz extremely low frequency electromagnetic fields enhance protein carbonyl groups content in cancer cells: effects on proteasomal systems},
year = {2009},
doi = {10.1155/2009/834239},
}