Morphological and antioxidant impairments in the spinal cord of male offspring rats following exposure to a continuous 900 MHz electromagnetic field during early and mid-adolescence
İkinci A, Mercantepe T, Unal D, Erol HS, Şahin A, Aslan A, Baş O, Erdem H, Sönmez OF, Kaya H, Odacı E. · 2016
View Original AbstractThe study results show that biochemical alterations and pathological changes may occur in the spinal cords of male rats following exposure to 900 MHz EMF for 1 hour daily from postnatal day 21 to 46.
Plain English Summary
The study began with 24 Sprague-Dawley male rats aged 3 weeks, divided equally into control, sham, and EMF exposure groups. EMF group rats were exposed to 900 MHz EMF for 1 hour daily from postnatal day 21 to 46. Biochemistry showed significantly increased malondialdehyde and glutathione in the EMF group versus control and sham, while catalase and superoxide dismutase were higher in both sham and EMF groups versus control. Light microscopy revealed spinal cord atrophy, vacuolization, myelin thickening, and perikarya irregularities in the EMF group. Transmission electron microscopy showed loss of myelin sheath integrity, invagination into the axon, and broad vacuoles in axoplasm.
Why This Matters
The aim of the study was to investigate changes in the spinal cords of male rat pups exposed to 900 MHz EMF. Sham rats were kept in the EMF cage for 1 hour without EMF exposure. After exposure, the upper thoracic spinal cords were removed and processed for biochemistry, light microscopy, and transmission electron microscopy.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 900MHz Duration: 1h a day between postnatal days 21-46
Study Details
The aim of this study was to investigate changes in the spinal cords of male rat pups exposed to the effect of 900MHz EMF.
The study began with 24 Sprague-Dawley male rats aged 3 weeks. Three groups containing equal numbers...
Biochemistry results revealed significantly increased malondialdehyde and glutathione levels in EMFG...
The study results show that biochemical alterations and pathological changes may occur in the spinal cords of male rats following exposure to 900MHz EMF for 1h a day on PD 21-46.
Show BibTeX
@article{a_2016_morphological_and_antioxidant_impairments_1501,
author = {İkinci A and Mercantepe T and Unal D and Erol HS and Şahin A and Aslan A and Baş O and Erdem H and Sönmez OF and Kaya H and Odacı E. },
title = {Morphological and antioxidant impairments in the spinal cord of male offspring rats following exposure to a continuous 900 MHz electromagnetic field during early and mid-adolescence},
year = {2016},
url = {https://www.sciencedirect.com/science/article/abs/pii/S0891061815000964},
}