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[Modeling of the effect of modulated electromagnetic radiation on animal cells].

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Gapeev AB, Chemeris NK · 2000

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Mathematical modeling shows 1 Hz electromagnetic radiation can increase cellular calcium levels by 50%, disrupting normal immune cell function.

Plain English Summary

Summary written for general audiences

Russian researchers created a mathematical model to understand how electromagnetic radiation affects calcium levels inside immune cells called neutrophils. They found that when the radiation frequency matched the cell's natural calcium signaling rhythm (around 1 Hz), it could increase calcium levels by more than 50%. This suggests that EMF exposure might disrupt normal cell function by interfering with the calcium signals that cells use to communicate and respond to their environment.

Why This Matters

This theoretical modeling study provides crucial insight into how EMF exposure might interfere with fundamental cellular processes. The researchers identified a specific mechanism - disruption of calcium signaling in immune cells - that could explain many of the biological effects observed in EMF research. What makes this particularly significant is that calcium acts as a universal cellular messenger, controlling everything from muscle contractions to gene expression. The finding that 1 Hz modulation can dramatically increase cellular calcium levels is especially relevant given that many modern wireless devices use similar low-frequency modulation patterns. While this was a modeling study rather than direct biological testing, it aligns with experimental data showing EMF effects on neutrophils, lending credibility to the proposed mechanism. This research helps bridge the gap between EMF exposure and measurable biological responses, offering a plausible explanation for how non-thermal EMF effects could occur at the cellular level.

Exposure Information

Specific exposure levels were not quantified in this study. The study examined exposure from: 1 Hz

Study Details

Frequency-dependent modifications of intracellular free calcium concentration ([Ca2+]i) in neutrophils exposures to modulated extremely high frequency electromagnetic radiation were analyzed using a special mathematical model for [Ca2+]i oscillations.

The model took into account the activation of Ca2+ influx into the cell by cytosolic Ca2+ and Ca(2+)...

The model simulation showed that in response to modulating signal, the rise in [Ca2+]i, has frequenc...

Thus, as the characteristic frequency of the quasi-periodic process of calcium signalling in the cell coincides with the frequency of external field, a narrow-band rise in [Ca2+]i is observed, which can result in a modification of the functional activity of the cell.

Cite This Study
Gapeev AB, Chemeris NK (2000). [Modeling of the effect of modulated electromagnetic radiation on animal cells]. Biofizika 45(2):299-312, 2000.
Show BibTeX
@article{ab_2000_modeling_of_the_effect_2100,
  author = {Gapeev AB and Chemeris NK},
  title = {[Modeling of the effect of modulated electromagnetic radiation on animal cells].},
  year = {2000},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/10776544/},
}

Quick Questions About This Study

Russian researchers created a mathematical model to understand how electromagnetic radiation affects calcium levels inside immune cells called neutrophils. They found that when the radiation frequency matched the cell's natural calcium signaling rhythm (around 1 Hz), it could increase calcium levels by more than 50%. This suggests that EMF exposure might disrupt normal cell function by interfering with the calcium signals that cells use to communicate and respond to their environment.