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Absence of 60-Hz, 0.1-mT magnetic field-induced changes in oncogene transcription rates or levels in CEM- CM3 cells

No Effects Found

Authors not listed · 1998

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Exposure to a 60-Hz, 0.1-mT magnetic field did not change transcription rates or transcript levels of c-fos, c-jun, or c-myc in CEM-CM3 cells.

Plain English Summary

Summary written for general audiences

Researchers assessed whether a 60-Hz magnetic field at 0.1 mT could reproduce earlier reported transcription changes in c-fos, c-jun, and c-myc oncogenes in CEM-CM3 cells. Cells were exposed for 15, 30, 60, or 120 minutes to the field or to a sham condition with coils in bucking mode. Transcription rates measured by nuclear run-on assay and transcript levels measured by Northern analysis showed no significant difference between exposed and sham or control cells at any time point.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 60 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 60 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Unknown (1998). Absence of 60-Hz, 0.1-mT magnetic field-induced changes in oncogene transcription rates or levels in CEM- CM3 cells.
Show BibTeX
@article{absence_of_60_hz_01_mt_magnetic_field_induced_changes_in_oncogene_transcription_rates_or_levels_in_cem_cm3_cells_ce1566,
  author = {Unknown},
  title = {Absence of 60-Hz, 0.1-mT magnetic field-induced changes in oncogene transcription rates or levels in CEM- CM3 cells},
  year = {1998},
  doi = {10.1016/S0167-4781(98)00238-3},
  
}

Quick Questions About This Study

The study aimed to assess the reproducibility of earlier reported 60-Hz magnetic field-induced transcription changes in c-fos, c-jun, and c-myc oncogenes in CEM-CM3 cells.
Cells were exposed to a 60-Hz magnetic field at 0.1 mT generated by Helmholtz coils in reinforcing mode, with a sham condition using coils in bucking mode.
Exposures lasted 15, 30, 60, or 120 minutes.
No significant difference was detected between magnetic field-exposed and sham or control cells for either transcription rates measured by nuclear run-on assay or transcript levels measured by Northern analysis at any time point.