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The 2100MHz radiofrequency radiation of a 3G-mobile phone and the DNA oxidative damage in brain.

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Şahin D, Özgür E, Güler G, Tomruk A, Ünlü İ, Sepici-Dinçel A, Seyhan N. · 2016

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Oxidative DNA damage in rat brains increased after 10 days of 2100 MHz radiofrequency exposure but was decreased compared to controls after 40 days.

Plain English Summary

Summary written for general audiences

The main finding was increased oxidative DNA damage in the brain after 10 days of exposure, while after 40 days oxidative DNA damage was decreased compared to control groups. A decreased level of the lipid peroxidation marker MDA was also observed after 40 days of exposure.

Why This Matters

The female rats were randomly divided into four groups, two exposed and two control, matched to the 10-day and 40-day time points. Oxidative DNA damage was measured as 8-hydroxy-2′deoxyguanosine (pg/mL) and malondialdehyde (MDA, nmoL/g tissue) levels were determined from brain tissue. The researchers suggested that the decreased damage seen at 40 days could reflect adapted and increased DNA repair mechanisms.

Exposure Details

SAR
0.4 W/kg
Electric Field
16 V/m
Source/Device
2100 MHz
Exposure Duration
Group I - 6 h/day, 5 consecutive days/wk for 2 weeks and Group IV- 6 h/day on 5 consecutive days/week for 8 weeks

Exposure Context

This study used 16 V/m for electric fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.4 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 4 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.10 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.10 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

We aimed to evaluate the effect of 2100 MHz radiofrequency radiation emitted by a generator, simulating a 3G-mobile phone on the brain of rats during 10 and 40 days of exposure

The female rats were randomly divided into four groups. Group I; exposed to 3G modulated 2100 MHz RF...

Our main finding was the increased oxidative DNA damage to brain after 10 days of exposure with the ...

The measured decreased quantities of damage during the 40 days of exposure could be the means of adapted and increased DNA repair mechanisms.

Cite This Study
Şahin D, Özgür E, Güler G, Tomruk A, Ünlü İ, Sepici-Dinçel A, Seyhan N. (2016). The 2100MHz radiofrequency radiation of a 3G-mobile phone and the DNA oxidative damage in brain. J Chem Neuroanat. 2016 Jan 8. pii: S0891-0618(16)00004-1. doi: 10.1016/j.jchemneu.2016.01.002.
Show BibTeX
@article{d_2016_the_2100mhz_radiofrequency_radiation_566,
  author = {Şahin D and Özgür E and Güler G and Tomruk A and Ünlü İ and Sepici-Dinçel A and Seyhan N.},
  title = {The 2100MHz radiofrequency radiation of a 3G-mobile phone and the DNA oxidative damage in brain.},
  year = {2016},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0891061816000041},
}

Quick Questions About This Study

Rats were exposed to 2100 MHz radiofrequency radiation from a generator simulating a 3G mobile phone, for 6 hours a day, 5 consecutive days per week.
Oxidative DNA damage in the brain was increased after 10 days of exposure compared to the control group.
After 40 days of exposure, oxidative DNA damage was decreased compared to the control group, and a decreased level of MDA was also observed.
The researchers suggested the lower damage at 40 days could reflect adapted and increased DNA repair mechanisms.
Oxidative DNA damage was measured as 8-hydroxy-2′deoxyguanosine (pg/mL) and malondialdehyde (MDA, nmoL/g tissue) levels were also determined.