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Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Brain & Nervous System

In Situ Expression of Heat-Shock Proteins and 3-Nitrotyrosine in Brains of Young Rats Exposed to a WiFi Signal In Utero and In Early Life

No Effects Found

Aït-Aïssa S, de Gannes FP, Taxile M, Billaudel B, Hurtier A, Haro E, Ruffié G, Athané A, Veyret B, Lagroye I · 2013

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Repeated WiFi exposure during gestation and early life showed no significant difference between exposed and sham-exposed young rats.

Plain English Summary

Summary written for general audiences

Researchers investigated bioeffects of WiFi signals on developing nervous systems of young rodents by assessing expression levels of 3-Nitrotyrosine, Hsp25, and Hsp70. Daily 2-hour exposures were performed blind in a reverberation chamber at whole-body specific absorption rates of 0, 0.08, 0.4, and 4 W/kg. No significant difference was observed among exposed and sham-exposed groups. The results suggest repeated WiFi exposure during gestation and early life has no deleterious effects on young rat brains.

Why This Matters

These biomarkers were measured in the brains of young rats exposed to a 2450 MHz WiFi signal by immunohistochemistry. 3-NT and stress protein expression was assayed in different areas of the hippocampus and cortex.

Exposure Details

SAR
0, 0.08, 0.4 and 4 W/kg
Source/Device
2450 MHz WiFi signal
Exposure Duration
daily 2h In utero(6 to day 21 of gestation) & daily 2h upto 5 weeks (New Borns per litter)

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kg
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.45 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.45 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

To Study the bioeffects of exposure to Wireless High-Fidelity (WiFi) signals on the developing nervous systems of young rodents was investigated by assessing the in vivo and in situ expression levels of three stress markers: 3-Nitrotyrosine (3-NT), an oxidative stress marker and two heat-shock proteins (Hsp25 and Hsp70).

These biomarkers were measured in the brains of young rats exposed to a 2450 MHz WiFi signal by immu...

No significant difference was observed among exposed and sham-exposed groups

These results suggest that repeated exposure to WiFi during gestation and early life has no deleterious effects on the brains of young rats.

Cite This Study
Aït-Aïssa S, de Gannes FP, Taxile M, Billaudel B, Hurtier A, Haro E, Ruffié G, Athané A, Veyret B, Lagroye I (2013). In Situ Expression of Heat-Shock Proteins and 3-Nitrotyrosine in Brains of Young Rats Exposed to a WiFi Signal In Utero and In Early Life Radiat Res (2013) 179 (6): 707–716.
Show BibTeX
@article{s_2013_in_situ_expression_of_2734,
  author = {Aït-Aïssa S and de Gannes FP and Taxile M and Billaudel B and Hurtier A and Haro E and Ruffié G and Athané A and Veyret B and Lagroye I},
  title = {In Situ Expression of Heat-Shock Proteins and 3-Nitrotyrosine in Brains of Young Rats Exposed to a WiFi Signal In Utero and In Early Life},
  year = {2013},
  
  url = {https://meridian.allenpress.com/radiation-research/article-abstract/179/6/707/149786},
}

Quick Questions About This Study

The study measured 3-Nitrotyrosine, an oxidative stress marker, and two heat-shock proteins, Hsp25 and Hsp70.
No significant difference was observed among exposed and sham-exposed groups.
Whole-body specific absorption rate levels were 0, 0.08, 0.4, and 4 W/kg.
3-NT and stress protein expression was assayed in different areas of the hippocampus and cortex.