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Endometrial Apoptosis Induced by a 900-MHz Mobile Phone: Preventive Effects of Vitamins E and C.

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Oral B, Guney M, Ozguner F, Karahan N, Mungan T, Comlekci S, Cesur G. · 2006

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Exposure to 900-MHz radiation emitted by mobile phones may cause endometrial apoptosis and oxidative stress in rats, but treatment with vitamins E and C can diminish these changes.

Plain English Summary

Summary written for general audiences

Researchers examined oxidative stress from a 900-MHz mobile phone and the possible protective effects of vitamins E and C on endometrial tissue in rats. Rats were divided into a sham control group, a 900-MHz EMF-exposed group (30 minutes daily for 30 days), and an EMF-exposed group treated with vitamins E and C before each exposure. Malondialdehyde, a marker of lipid peroxidation, and the proteins Bcl-2, Bax, caspase-3, and caspase-8 were measured in endometrial tissue. The EMF-exposed rats showed increased malondialdehyde levels and apoptosis, while vitamins E and C ameliorated oxidative tissue injury and apoptosis through free radical scavenging and antioxidant properties.

Why This Matters

The study concluded that exposure to 900-MHz radiation emitted by mobile phones may cause endometrial apoptosis and oxidative stress in rats. The researchers also stated that treatment with vitamins E and C can diminish these changes and may have a beneficial effect in preventing endometrial changes.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 900 MHz Duration: 30 min/d for 30 d

Study Details

The purposes of this study were to examine oxidative stress that promotes production of reactive oxygen species induced by a 900-megahertz (MHz) mobile phone and the possible ameliorating effects of vitamins E and C on endometrial tissue against EMF-induced endometrial impairment and apoptosis in rats.

Animals were randomly grouped as follows: (1) sham-operated control group (n=8), (2) 900 MHz EMF-exp...

In this study, increased malondialdehyde levels in endometrial tissue and apoptosis illustrated the ...

In conclusion, exposure to 900-MHz radiation emitted by mobile phones may cause endometrial apoptosis and oxidative stress, but treatment with vitamins E and C can diminish these changes and may have a beneficial effect in preventing endometrial changes in rats.

Cite This Study
Oral B, Guney M, Ozguner F, Karahan N, Mungan T, Comlekci S, Cesur G. (2006). Endometrial Apoptosis Induced by a 900-MHz Mobile Phone: Preventive Effects of Vitamins E and C. Adv Ther. 23(6):957-973, 2006.
Show BibTeX
@article{b_2006_endometrial_apoptosis_induced_by_1685,
  author = {Oral B and Guney M and Ozguner F and Karahan N and Mungan T and Comlekci S and Cesur G.},
  title = {Endometrial Apoptosis Induced by a 900-MHz Mobile Phone: Preventive Effects of Vitamins E and C.},
  year = {2006},
  doi = {10.1007/BF02850217},
  url = {https://link.springer.com/article/10.1007/BF02850217},
}
DOI: 10.1007/BF02850217

Cited By (119 papers)

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Quick Questions About This Study

Rats were exposed to 900 MHz EMF for 30 minutes daily for 30 days.
Exposed rats showed increased malondialdehyde levels and apoptosis in endometrial tissue, while vitamins E and C reduced oxidative tissue injury and apoptosis.
Vitamins E and C ameliorated oxidative tissue injury and apoptosis through free radical scavenging and antioxidant properties.
Malondialdehyde was used as a marker of lipid peroxidation, and Bcl-2, Bax, caspase-3, and caspase-8 were assessed immunohistochemically.
Vitamin E was given at 50 mg/kg intramuscularly and vitamin C at 20 mg/kg intraperitoneally before daily EMF exposure.