Effects of a 900-MHz electromagnetic field on oxidative stress parameters in rat lymphoid organs, polymorphonuclear leukocytes and plasma.
Aydin B, Akar A. · 2011
View Original AbstractExposure to a 900-MHz electromagnetic field reduced antioxidant defenses and increased oxidative stress markers in rats, with greater irreversible damage in immature rats than in mature rats.
Plain English Summary
Researchers exposed immature and mature rats to a 900-MHz electromagnetic field for 2 hours per day for 45 days and measured oxidative stress in lymphoid organs, polymorphonuclear leukocytes, and plasma. Antioxidant enzyme activity, glutathione levels in lymphoid organs, and the antioxidant capacity of plasma decreased after exposure, while lipid peroxidation, nitric oxide levels, and myeloperoxidase activity increased. Improvements seen after a recovery period were limited, especially in immature rats, and oxidative damage was described as tissue specific.
Why This Matters
The field strength used in the exposure was 28.2 ± 2.1 V/m at 900 MHz. Recovery groups were observed for 15 days after EMF exposure ended to assess whether any damage could reverse. The study tested whether EMF-induced damage is reversible in immature and mature rats. The researchers found that much higher levels of irreversible oxidative damage appeared in the major lymphoid organs of immature rats compared with mature rats.
Exposure Details
- Electric Field
- 28.2 ± 2.1 V/m
- Source/Device
- 900-MHz
- Exposure Duration
- 2 h/day for 45 days
Exposure Context
This study used 28.2 ± 2.1 V/m for electric fields:
- 7x above the Building Biology guideline of 0.3 V/m
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Study Details
The present study investigated the effects of a 900-MHz electromagnetic field (EMF) for 2 h/day for 45 days on lymphoid organs (spleen, thymus, bone marrow), polymorphonuclear leukocytes (PMNs) and plasma of rats, focusing on changes in the enzymatic and nonenzymatic antioxidant system. We determined whether there is any difference between immature and mature rats in terms of oxidative damage caused by EMF and tested recovery groups to determine whether EMF-induced damage is reversible in immature and mature rats.
Twenty four immature and 24 mature rats were divided randomly and equally into six groups as follows...
Substantial, deleterious biochemical changes were observed in oxidative stress metabolism after EMF ...
In the present study, much higher levels of irreversible oxidative damage were observed in the major lymphoid organs of immature rats than in mature rats.
Show BibTeX
@article{b_2011_effects_of_a_900mhz_831,
author = {Aydin B and Akar A.},
title = {Effects of a 900-MHz electromagnetic field on oxidative stress parameters in rat lymphoid organs, polymorphonuclear leukocytes and plasma.},
year = {2011},
url = {https://www.sciencedirect.com/science/article/abs/pii/S0188440911001196},
}