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BIOLOGICAL EFFECTS IN RODENTS EXPOSED TO PULSED ELECTROMAGNETIC RADIATION

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W. D. Skidmore, S. J. Baum · 1973

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Rodents exposed to electromagnetic pulses of 447 kV/m for 20 weeks showed no apparent acute injuries.

Plain English Summary

Summary written for general audiences

This 1973 Armed Forces Radiobiology Research Institute report exposed rodents to electromagnetic pulse (EMP) radiation, five pulses per second at a peak electric field intensity of 447 kV/m, during 20 weeks of nearly continuous exposure. Bone marrow, blood, chromosome, embryology, histology, leukemia, and mammary tumor assays indicated no apparent acute injuries. Reticulocyte counts in exposed rats were nearly always greater than in nonexposed rats, and platelet counts occasionally were lower.

Why This Matters

This 1973 report tested the hypothesis that rapid changes in electric and magnetic fields would induce injuries in biological systems with high cell turnover rates, such as bone marrow and the embryo. The exposure exceeded by several orders of magnitude the conditions normally encountered by humans who operate EMP facilities, and the exposed rodents showed no apparent acute injuries. Reticulocyte counts in exposed rats were nearly always greater than in nonexposed rats, and platelet counts occasionally were decreased.

The authors note that, because the experiment ran for only 20 weeks after the onset of exposure, no assessment could be made of late somatic effects such as tumors and cancers. They suggest that existing proposed safety standards might be reevaluated, particularly in regard to acute effects.

Finding

Exposures of rodents under these conditions indicated no apparent acute injuries. A tentative prediction can be made that humans exposed to EMP in industrial situations would show no acute biological injuries.

In their words

“Exposures of rodents under these conditions indicated no apparent acute injuries. A tentative prediction can be made that humans exposed to EMP in industrial situations would show no acute biological injuries.”

Exposure Details

Electric Field
447 kV/m
Exposure Duration
20 weeks

Exposure Context

This study used 447 kV/m for electric fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Study Details

To test the hypothesis that rapid changes in electric and magnetic fields would induce injuries in biological systems with high cell turnover rates.

The AFRRI EMP simulator provided five pulses per second with a peak electric field intensity of 447 ...

The reticulocyte count in exposed rats was nearly always greater than in nonexposed. However, there ...

Exposures of rodents under these conditions indicated no apparent acute injuries. A tentative prediction can be made that humans exposed to EMP in industrial situations would show no acute biological injuries. It is suggested that existing safety standards might be reevaluated, particularly in regard to acute effects. However, since the present experiment has been conducted for only 20 weeks after the onset of EMP radiation exposure, no assessment could be made for the appearance of late somatic effects (e.g., tumors and cancers) possibly induced early by damage at the molecular level.

Cite This Study
W. D. Skidmore, S. J. Baum (1973). BIOLOGICAL EFFECTS IN RODENTS EXPOSED TO PULSED ELECTROMAGNETIC RADIATION.
Show BibTeX
@article{biological_effects_in_rodents_exposed_to_pulsed_electromagnetic_radiation_g6846,
  author = {W. D. Skidmore and S. J. Baum},
  title = {BIOLOGICAL EFFECTS IN RODENTS EXPOSED TO PULSED ELECTROMAGNETIC RADIATION},
  year = {1973},
  
  
}
No DOI on file for this study.

Quick Questions About This Study

The AFRRI EMP simulator provided five pulses per second with a peak electric field intensity of 447 kV/m, a 5 nsec rise time, and a 5-600 nsec 1/e fall time. Exposures were continuous except for about 1 hour daily for biological sampling and animal care during 20 weeks.
Male Sprague-Dawley rats, pregnant rats, and female rats observed for mammary tumors were exposed, along with leukemia-prone AKR/J mice, and each group was compared with nonexposed animals.
The authors made a tentative prediction that humans exposed to EMP in industrial situations would show no acute biological injuries, noting that the experiment exceeded conditions normally encountered by humans who operate EMP facilities by several orders of magnitude. No assessment could be made of late effects such as tumors and cancers.
The study measured blood counts, bone marrow cellularity, chromosome aberrations, radioactive iron incorporation, blood chemistry, embryology, histology, leukemia, and mammary tumors. Exposures indicated no apparent acute injuries, although reticulocyte counts in exposed rats were nearly always greater and platelet counts occasionally were lower than in nonexposed rats.
Proposed safety standards assumed a biological hazard exists and would restrict healthy workers to 50 kV/m at one pulse per minute, while the authors state there were not enough biological data to support these standards. The experiment tested whether EMP damages systems with high cellular turnover.