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Interactive developmental toxicity of radiofrequency radiation and 2-methoxyethanol in rats.

No Effects Found

Nelson BK, Conover DL, Shaw PB, Werren DM, Edwards RM, Hoberman AM · 1994

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Radiofrequency radiation can amplify chemical toxicity during pregnancy, causing enhanced birth defects at intermediate exposure levels.

Plain English Summary

Summary written for general audiences

Researchers exposed pregnant rats to radiofrequency radiation (10 MHz) combined with an industrial solvent called 2-methoxyethanol to see if the combination caused more birth defects than either exposure alone. They found that when combined, these exposures produced enhanced developmental damage to limbs and digits in rat fetuses, particularly when exposure occurred on day 13 of pregnancy. This suggests that EMF radiation can amplify the harmful effects of certain chemical exposures during pregnancy.

Study Details

We previously demonstrated that combined exposure to radiofrequency (RF; 10 MHz) radiation, which also induces hyperthermia and is teratogenic to exposed animals, and the industrial solvent, 2-methoxyethanol (2ME), produces enhanced teratogenicity in rats. The present study replicates and extends the previous research investigating the enhanced teratogenicity of combined RF radiation and 2ME exposures.

The interactive dose-related teratogenicity of RF radiation (sham exposure or maintaining colonic te...

The results are consistent with and extend our previous research findings. Synergism was observed be...

Statistical analyses did not show a global synergistic effect, but did show evidence for a synergistic effect at intermediate levels of the dose ranges. Future research will address potential interactions at lower doses.

Cite This Study
Nelson BK, Conover DL, Shaw PB, Werren DM, Edwards RM, Hoberman AM (1994). Interactive developmental toxicity of radiofrequency radiation and 2-methoxyethanol in rats. Teratology 50(4):275-293, 1994.
Show BibTeX
@article{bk_1994_interactive_developmental_toxicity_of_3270,
  author = {Nelson BK and Conover DL and Shaw PB and Werren DM and Edwards RM and Hoberman AM},
  title = {Interactive developmental toxicity of radiofrequency radiation and 2-methoxyethanol in rats.},
  year = {1994},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/7716735/},
}

Quick Questions About This Study

Researchers exposed pregnant rats to radiofrequency radiation (10 MHz) combined with an industrial solvent called 2-methoxyethanol to see if the combination caused more birth defects than either exposure alone. They found that when combined, these exposures produced enhanced developmental damage to limbs and digits in rat fetuses, particularly when exposure occurred on day 13 of pregnancy. This suggests that EMF radiation can amplify the harmful effects of certain chemical exposures during pregnancy.