6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.
Shield Your Body

Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Brain & Nervous System

Effects of 50 Hz electromagnetic fields on rat cortical synaptosomes

No Effects Found

Aldinucci C, Carretta A, Maiorca SM, Leoncini S, Signorini C, Ciccoli L, Pessina GP · 2009

View Original Abstract
Share:

The physiological behavior of cortical synaptosomes was unaffected by weak pulsed electromagnetic fields.

Plain English Summary

Summary written for general audiences

Researchers exposed synaptosomes to a peak magnetic field of 2 mT for 2 hours. They evaluated mitochondrial respiration rate, ATP production, membrane potential, intrasynaptosomal calcium concentration, and release of free iron and F2-isoprostanes. Oxygen consumption and ATP production remained unchanged in exposed synaptosomes. Intrasynaptosomal calcium concentration decreased slowly with no membrane depolarization detected, and free iron and F2-isoprostane release remained unchanged.

Exposure Details

Magnetic Field
2 mT
Source/Device
50 Hz
Exposure Duration
2-h

Exposure Context

This study used 2 mT for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 2 mTExtreme Concern - 5 mGFCC Limit - 2,000 mGEffects observed in the Extreme Concern range (Building Biology)This level is 10 times the FCC limit
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 50 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 50 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Study Details

The present study examined the effect of a 2-h exposure of synaptosomes on a system generating a peak magnetic field of 2 mT.

We evaluated the changes of the synaptosomal mitochondrial respiration rate and ATP production, memb...

The intrasynaptosomal Ca2+ concentration decreased slowly and no depolarization of the synaptosomal...

These results indicate that the physiological behavior of cortical synaptosomes was unaffected by weak pulsed EMFs.

Cite This Study
Aldinucci C, Carretta A, Maiorca SM, Leoncini S, Signorini C, Ciccoli L, Pessina GP (2009). Effects of 50 Hz electromagnetic fields on rat cortical synaptosomes Toxicol Ind Health. 25(4-5):249-252, 2009.
Show BibTeX
@article{c_2009_effects_of_50_hz_2822,
  author = {Aldinucci C and Carretta A and Maiorca SM and Leoncini S and Signorini C and Ciccoli L and Pessina GP},
  title = {Effects of 50 Hz electromagnetic fields on rat cortical synaptosomes},
  year = {2009},
  doi = {10.1177/0748233709103031},
  url = {https://journals.sagepub.com/doi/abs/10.1177/0748233709103031},
}
DOI: 10.1177/0748233709103031

Cited By (17 papers)

Quick Questions About This Study

Synaptosomes were exposed for 2 hours to a system generating a peak magnetic field of 2 mT.
The study measured mitochondrial respiration rate, ATP production, membrane potential, intrasynaptosomal calcium concentration, and release of free iron and F2-isoprostanes.
Oxygen consumption and ATP production remained unchanged in exposed synaptosomes.
Intrasynaptosomal calcium concentration decreased slowly and no depolarization of the synaptosomal membrane was detected.
The physiological behavior of cortical synaptosomes was unaffected by weak pulsed electromagnetic fields.