Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.
Extremely Low-Frequency Magnetic Exposure Appears to Have No Effect on Pathogenesis of Alzheimer’s Disease in Aluminum-Overloaded Rat
Zhang C, Li Y, Wang C, Lv R, Song T · 2013
View Original AbstractELF-MF exposure at 100 µT and 50 Hz showed no effect on Alzheimer's disease pathogenesis in rats, with or without aluminum overload.
Plain English Summary
Researchers exposed Sprague-Dawley rats to ELF-MF at 100 µT and 50 Hz with or without oral aluminum for 12 weeks. Oral aluminum treatment caused learning and memory impairment, neuronal cell loss, and high amyloid-β density in the hippocampus and cerebral cortex. ELF-MF alone showed no significant effect on Alzheimer's disease pathogenesis. Combined ELF-MF and aluminum exposure did not cause more damage than aluminum alone.
Why This Matters
The study was designed to test whether ELF-MF and aluminum have synergistic effects on Alzheimer's disease pathogenesis. The researchers found no evidence linking ELF-MF exposure at 100 µT and 50 Hz to Alzheimer's disease, and ELF-MF did not alter the disease process caused by aluminum overload.
Exposure Details
- Magnetic Field
- 0.1 mT
- Source/Device
- 50 Hz
- Exposure Duration
- 12 weeks
Exposure Context
This study used 0.1 mT for magnetic fields:
- 5Kx above the Building Biology guideline of 0.2 mG
- 1Kx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
This study aims to examine whether or not ELF-MF and Al have synergistic effects toward AD pathogenesis by investigating the effects of ELF-MF with or without chronic Al treatment on SD rats
Sprague-Dawley (SD) rats were subjected one of the following treatments: sham (control group), oral ...
After 12 wk of treatment, oral Al treatment groups (Al and MF+Al groups) showed learning and memory ...
Our results showed no evidence of any association between ELF-MF exposure (100 µT at 50 Hz) and AD, and ELF-MF exposure does not influence the pathogenesis of AD induced by Al overload.
Show BibTeX
@article{c_2013_extremely_lowfrequency_magnetic_exposure_2834,
author = {Zhang C and Li Y and Wang C and Lv R and Song T},
title = {Extremely Low-Frequency Magnetic Exposure Appears to Have No Effect on Pathogenesis of Alzheimer’s Disease in Aluminum-Overloaded Rat},
year = {2013},
url = {https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071087},
}