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Effects of Pulsed 2.856 GHz Microwave Exposure on BM-MSCs Isolated from C57BL/6 Mice.

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Wang C, Wang X, Zhou H, Dong G, Guan X, Wang L, Xu X, Wang S, Chen P, Peng R, Hu X. · 2015

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Microwave radiation at twice current US phone limits altered bone-forming genes in stem cells without killing the cells.

Plain English Summary

Summary written for general audiences

Researchers exposed mouse bone marrow stem cells to 2.856 GHz microwave radiation. While cells remained healthy and continued dividing normally, the radiation reduced expression of genes crucial for bone formation, suggesting microwaves can affect cellular function even without visible damage.

Why This Matters

This study reveals a concerning pattern we see repeatedly in EMF research: effects at the genetic level that occur without obvious cellular damage. The 4 W/kg exposure level used here is significant - it's twice the current SAR limit for cell phones in the United States (2 W/kg) and four times the European limit (2 W/kg). What makes this particularly important is that bone marrow stem cells are responsible for creating new bone tissue throughout your life. The reduced expression of bone-forming genes suggests that microwave exposure could potentially interfere with bone health and repair processes. The researchers themselves noted these were 'undefined adverse effects,' acknowledging that genetic changes in stem cells could have long-term consequences we don't yet fully understand. This adds to the growing body of evidence that current safety standards, which only consider heating effects, may not adequately protect against biological impacts occurring at the cellular and genetic levels.

Exposure Details

SAR
4 W/kg
Source/Device
2.856 GHz

Exposure Context

This study used 4 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 4 W/kgExtreme Concern0.1 W/kgFCC Limit1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 0x higher than this exposure level

Study Details

The aim of this study is to investigate Effects of Pulsed 2.856 GHz Microwave Exposure on BM-MSCs Isolated from C57BL/6 Mice.

n this study, the potential cytotoxicity on MSC proliferation, apoptosis, cell cycle, and in vitro d...

. Importantly, our findings indicated no significant changes in cell viability, cell division and ap...

These findings suggest that microwave treatment at a SAR of 4 W/kg has undefined adverse effects on BM-MSCs. However, the reduced-expression of proteins related to osteogenic differentiation suggests that microwave can the influence at the mRNA expression genetic level.

Cite This Study
Wang C, Wang X, Zhou H, Dong G, Guan X, Wang L, Xu X, Wang S, Chen P, Peng R, Hu X. (2015). Effects of Pulsed 2.856 GHz Microwave Exposure on BM-MSCs Isolated from C57BL/6 Mice. PLoS One. 2015 Feb 6;10(2):e0117550. doi: 10.1371/journal.pone.0117550. eCollection 2015.
Show BibTeX
@article{c_2015_effects_of_pulsed_2856_1420,
  author = {Wang C and Wang X and Zhou H and Dong G and Guan X and Wang L and Xu X and Wang S and Chen P and Peng R and Hu X.},
  title = {Effects of Pulsed 2.856 GHz Microwave Exposure on BM-MSCs Isolated from C57BL/6 Mice.},
  year = {2015},
  
  url = {https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117550},
}

Quick Questions About This Study

Researchers exposed mouse bone marrow stem cells to 2.856 GHz microwave radiation. While cells remained healthy and continued dividing normally, the radiation reduced expression of genes crucial for bone formation, suggesting microwaves can affect cellular function even without visible damage.