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Cell type-specific genotoxic effects of intermittent extremely low-frequency electromagnetic fields

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Authors not listed · 2005

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Intermittent 50 Hz, 1 mT ELF-EMF exposure for 1-24 hours caused DNA strand breaks in human fibroblasts, human melanocytes, and rat granulosa cells but not in human lymphocytes, monocytes, or skeletal muscle cells.

Plain English Summary

Summary written for general audiences

Researchers exposed cultured cells from different tissues to intermittent 50 Hz, 1 mT ELF-EMF for 1-24 hours. They used alkaline and neutral comet assays to assess ELF-EMF-induced DNA strand breaks. The study identified three responder cell types (human fibroblasts, human melanocytes, rat granulosa cells) and three non-responder cell types (human lymphocytes, human monocytes, human skeletal muscle cells).

Why This Matters

The authors noted that the issue of adverse health effects of extremely low-frequency electromagnetic fields is highly controversial. They concluded that the cell system used is significant when investigating genotoxic effects of ELF-EMF.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 50 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 50 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Unknown (2005). Cell type-specific genotoxic effects of intermittent extremely low-frequency electromagnetic fields.
Show BibTeX
@article{cell_type_specific_genotoxic_effects_of_intermittent_extremely_low_frequency_electromagnetic_fields_ce1470,
  author = {Unknown},
  title = {Cell type-specific genotoxic effects of intermittent extremely low-frequency electromagnetic fields},
  year = {2005},
  doi = {10.1016/J.MRGENTOX.2005.03.011},
  
}

Quick Questions About This Study

The study used intermittent 50 Hz sinusoidal ELF-EMF at 1 mT for 1-24 hours.
Human fibroblasts, human melanocytes, and rat granulosa cells showed DNA strand breaks.
Human lymphocytes, human monocytes, and human skeletal muscle cells did not show DNA strand breaks.
Alkaline and neutral comet assays were used to assess DNA strand breaks.
The authors concluded that the cell system used is significant when investigating genotoxic effects of ELF-EMF.