Continuous Exposure to 1.7 GHz LTE Electromagnetic Fields Increases Intracellular Reactive Oxygen Species to Decrease Human Cell Proliferation and Induce Senescence
Choi J, Min K, Jeon S, Kim N, Pack JK, Song K · 2020
Continuous exposure to 1.7 GHz LTE RF-EMF for 72 hours at 1 and 2 SAR reduced proliferation in all tested human cells, induced senescence in ASCs and Huh7 cells at 2 SAR, and increased intracellular ROS in those cells.
Plain English Summary
Researchers exposed multiple human cell types, including adipose-derived stem cells, liver cancer stem cells, HeLa, SH-SY5Y, and IMR-90 fibroblasts, to 1.7 GHz LTE RF-EMF continuously for 72 hours at 1 and 2 SAR. Cell proliferation decreased in all cell types, with a stronger effect at 2 SAR than at 1 SAR and a milder effect in adipose-derived stem cells. Exposure did not cause DNA double-strand breaks or apoptosis but caused a slight G1-to-S cell-cycle delay, and senescence appeared in ASCs and Huh7 cells at 2 SAR, accompanied by increased intracellular ROS that mediated the anti-proliferative effect.
Why This Matters
The authors note that widespread mobile phone use leads to continuous exposure to 1.7 GHz LTE RF-EMF, yet the biological effects remain unclear. They state that the observations strongly suggest the RF-EMF decreases proliferation and increases senescence by increasing intracellular ROS in human cells.
Show BibTeX
@article{choi_j_min_k_jeon_s_kim_n_pack_jk_song_k_ce2342,
author = {Choi J and Min K and Jeon S and Kim N and Pack JK and Song K},
title = {Continuous Exposure to 1.7 GHz LTE Electromagnetic Fields Increases Intracellular Reactive Oxygen Species to Decrease Human Cell Proliferation and Induce Senescence},
year = {2020},
}