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Experimental model for ELF-EMF exposure: Concern for human health

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D'Angelo C et al · 2015

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Preliminary results showed that EMF exposure differently modifies MCP-1 expression in different cell types.

Plain English Summary

Summary written for general audiences

Researchers studied MCP-1 expression in HaCaT, SH-SY5Y, THP-1, and K562 cells exposed to a sinusoidal EMF at 50 Hz with a flux density of 1 mT (rms). Preliminary results showed that EMF exposure differently modifies MCP-1 expression in different cell types. The authors state that MCP-1 expression needs to be better determined with additional studies using different parameters and exposure times.

Why This Matters

Epidemiological studies on EMF as a health risk factor have led to controversial results. MCP-1 is a chemokine that regulates migration of memory T cells, natural killer cells, monocytes, and epithelial cells and is involved in various diseases.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 50 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 50 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
D'Angelo C et al (2015). Experimental model for ELF-EMF exposure: Concern for human health.
Show BibTeX
@article{dangelo_c_et_al_january_2015_experimental_model_for_elf_emf_exposure_concern_for_human_health_saudi_j_biol_sci_2015_jan22175_84_doi_101016jsjbs201407006_ce1312,
  author = {D'Angelo C et al},
  title = {Experimental model for ELF-EMF exposure: Concern for human health},
  year = {2015},
  doi = {10.1016/j.sjbs.2014.07.006},
  
}
DOI: 10.1016/j.sjbs.2014.07.006PubMed: 25561888

Quick Questions About This Study

The study examined MCP-1 expression in HaCaT keratinocytes, SH-SY5Y neuroblastoma cells, THP-1 monocytic cells, and K562 leukemic cells.
Cells were exposed to a sinusoidal EMF at 50 Hz frequency with a flux density of 1 mT (rms).
Preliminary results showed that EMF exposure differently modifies MCP-1 expression in different cell types.
The authors state that MCP-1 expression needs to be better determined with additional studies using different parameters and exposure times.
MCP-1 is a chemokine that regulates migration of memory T cells, natural killer cells, monocytes, and epithelial cells and has been shown to be induced and involved in various diseases.