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ELF magnetic fields tuned to ion parametric resonance conditions do not affect TEA-sensitive voltage-dependent outward K(+) currents in a human neural cell line.

No Effects Found

Gavoçi E, Zironi I, Remondini D, Virelli A, Castellani G, Del Re B, Giorgi G, Aicardi G, Bersani F. · 2013

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Magnetic fields tuned for ion resonance showed no effect on brain cell potassium channels, but broader cellular mechanisms remain under investigation.

Plain English Summary

Summary written for general audiences

Researchers tested whether extremely low frequency magnetic fields could affect potassium channels in human brain cells by using specific field combinations designed to trigger 'ion parametric resonance' - a theoretical mechanism where magnetic fields might interfere with how ions move through cell membranes. They found no changes in potassium channel activity during or after exposure, suggesting these particular magnetic field conditions don't disrupt this specific type of cellular communication in brain cells.

Study Details

We studied the effect of different combinations of static (DC) and alternating (AC) ELF MFs tuned on resonance conditions for potassium (K+) on TEA-sensitive voltage-dependent outward K+ currents in the human neuroblastoma BE(2)C cell line.

Currents through the cell membrane were measured by whole-cell patch clamp before, during, and after...

No significant changes in K+ current density were found.

This study does not confirm the IPR hypothesis at the level of TEA-sensitive voltage-dependent outward K+ currents in our experimental conditions. However, this is not a direct disprove of the hypothesis, which should be investigated on other ion channels and at single channel levels also.

Cite This Study
Gavoçi E, Zironi I, Remondini D, Virelli A, Castellani G, Del Re B, Giorgi G, Aicardi G, Bersani F. (2013). ELF magnetic fields tuned to ion parametric resonance conditions do not affect TEA-sensitive voltage-dependent outward K(+) currents in a human neural cell line. Bioelectromagnetics. 34(8):579-88, 2013.
Show BibTeX
@article{e_2013_elf_magnetic_fields_tuned_2895,
  author = {Gavoçi E and Zironi I and Remondini D and Virelli A and Castellani G and Del Re B and Giorgi G and Aicardi G and Bersani F.},
  title = {ELF magnetic fields tuned to ion parametric resonance conditions do not affect TEA-sensitive voltage-dependent outward K(+) currents in a human neural cell line.},
  year = {2013},
  doi = {10.1002/bem.21807},
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/bem.21807},
}

Quick Questions About This Study

Researchers tested whether extremely low frequency magnetic fields could affect potassium channels in human brain cells by using specific field combinations designed to trigger 'ion parametric resonance' - a theoretical mechanism where magnetic fields might interfere with how ions move through cell membranes. They found no changes in potassium channel activity during or after exposure, suggesting these particular magnetic field conditions don't disrupt this specific type of cellular communication in brain cells.