Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.
Acute exposure to low-level CW and GSM-modulated 900 MHz radiofrequency does not affect Ba 2+ currents through voltage-gated calcium channels in rat cortical neurons.
Platano D, Mesirca P, Paffi A, Pellegrino M, Liberti M, Apollonio F, Bersani F, Aicardi G · 2007
View Original AbstractAcute exposure to low-level 900 MHz radiofrequency fields, either continuous wave or GSM-modulated, did not significantly alter barium currents through voltage-gated calcium channels in rat cortical neurons.
Plain English Summary
Researchers studied the non-thermal effects of radiofrequency electromagnetic fields on barium currents through voltage-gated calcium channels in primary cultures of rat cortical neurons using the patch-clamp technique. Neurons were exposed for one to three periods of 90 seconds to 900 MHz continuous wave or GSM-modulated signals during whole-cell recording at specific absorption rates of 2 W/kg for both modulation types. Single or multiple acute exposures to either continuous wave or GSM-modulated 900 MHz fields did not significantly alter the current amplitude or the current-voltage relationship through voltage-gated calcium channels.
Exposure Details
- SAR
- 2 W/kg
- Source/Device
- GSM‐modulated 900 MHz
Exposure Context
This study used 2 W/kg for SAR (device absorption):
- 5x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
We have studied the non‐thermal effects of radiofrequency (RF) electromagnetic fields (EMFs) on Ba2+ currents (equation image) through voltage‐gated calcium channels (VGCC), recorded in primary cultures of rat cortical neurons using the patch‐clamp technique.
To assess whether low‐level acute RF field exposure could modify the amplitude and/or the voltage‐de...
The results obtained indicate that single or multiple acute exposures to either CW or GSM‐modulated ...
Show BibTeX
@article{d_2007_acute_exposure_to_lowlevel_2795,
author = {Platano D and Mesirca P and Paffi A and Pellegrino M and Liberti M and Apollonio F and Bersani F and Aicardi G},
title = {Acute exposure to low-level CW and GSM-modulated 900 MHz radiofrequency does not affect Ba 2+ currents through voltage-gated calcium channels in rat cortical neurons.},
year = {2007},
doi = {10.1002/bem.20345},
url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/bem.20345},
}Cited By (38 papers)
- Considerations for Developing an RF Exposure System: A Review for in vitro Biological Experiments
A. Paffi et al. (2010) - 90 citations
- Review of possible modulation‐dependent biological effects of radiofrequency fields
J. Juutilainen et al. (2011) - 78 citations
- Cognitive effects of radiation emitted by cellular phones: The influence of exposure side and time
R. Luria et al. (2009) - 75 citations
- Electromagnetic radiation (Wi-Fi) and epilepsy induce calcium entry and apoptosis through activation of TRPV1 channel in hippocampus and dorsal root ganglion of rats
V. Ghazizadeh, M. Nazıroğlu (2014) - 65 citations
- Effects of electromagnetic fields on neuronal ion channels: a systematic review
Federico Bertagna et al. (2021) - 60 citations
- Assessment of Cytoplasm Conductivity by Nanosecond Pulsed Electric Fields
A. Denzi et al. (2015) - 45 citations
- Real-Time RF Exposure Setup Based on a Multiple Electrode Array (MEA) for Electrophysiological Recording of Neuronal Networks
Caterina Merla et al. (2011) - 40 citations
- Scientific Committee on Emerging and Newly Identified Health Risks SCENIHR Health
P. Hartemann et al. (2009) - 37 citations
- A Real-Time Exposure System for Electrophysiological Recording in Brain Slices
A. Paffi et al. (2007) - 31 citations