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Mobile phone radiofrequency exposure has no effect on DNA double strand breaks (DSB) in human lymphocytes.

No Effects Found

Danese E, Lippi G, Buonocore R, Benati M, Bovo C, Bonaguri C, Salvagno GL, Brocco G, Roggenbuck D, Montagnana M. · 2017

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Exposure of human lymphocytes to 900 MHz radiofrequency from a commercial mobile phone for 30 minutes did not significantly impact DNA integrity.

Plain English Summary

Summary written for general audiences

Researchers exposed blood samples from 14 healthy volunteers to 900 MHz radiofrequency from a commercial mobile phone for 30 minutes. A control sample was kept away from radiofrequency sources. DNA integrity was measured by analyzing γ-H2AX foci in lymphocytes using immunofluorescence staining. No measure of γ-H2AX foci was significantly influenced by the exposure, and the odds ratio for genetic damage ranged from 0.27 to 1.00.

Why This Matters

The study aimed to investigate the potential genotoxic effect of mobile phone radiofrequency exposure on human peripheral blood mononuclear cells in vitro. The exposed blood sample was positioned 1 cm from the phone chassis during a 30-minute call at 900 MHz.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 900 MHz Duration: 30 minutes call

Study Details

This study was aimed to investigate the potential genotoxic effect of mobile phone radiofrequency exposure on human peripheral blood mononuclear cells in vitro.

The study population consisted in 14 healthy volunteers. After collection of two whole blood samples...

No measure of γ-H2AX foci was significantly influenced by mobile phone RF exposure, nor mobile phone...

The results of this experimental study demonstrate that exposure of human lymphocytes to a conventional 900 MHz RF emitted by a commercial mobile phone for 30 min does not significantly impact DNA integrity.

Cite This Study
Danese E, Lippi G, Buonocore R, Benati M, Bovo C, Bonaguri C, Salvagno GL, Brocco G, Roggenbuck D, Montagnana M. (2017). Mobile phone radiofrequency exposure has no effect on DNA double strand breaks (DSB) in human lymphocytes. Ann Transl Med. 5(13):272, 2017.
Show BibTeX
@article{e_2017_mobile_phone_radiofrequency_exposure_2992,
  author = {Danese E and Lippi G and Buonocore R and Benati M and Bovo C and Bonaguri C and Salvagno GL and Brocco G and Roggenbuck D and Montagnana M.},
  title = {Mobile phone radiofrequency exposure has no effect on DNA double strand breaks (DSB) in human lymphocytes.},
  year = {2017},
  
  url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515807/},
}

Quick Questions About This Study

The study aimed to investigate the potential genotoxic effect of mobile phone radiofrequency exposure on human peripheral blood mononuclear cells in vitro.
One blood sample was placed 1 cm from a commercial mobile phone operating at 900 MHz during a 30-minute call, while the other sample was kept far from radiofrequency sources.
DNA integrity was assessed by analyzing γ-H2AX foci in lymphocytes using an immunofluorescence staining kit on AKLIDES.
No measure of γ-H2AX foci was significantly influenced by the exposure, and the odds ratio for genetic damage ranged from 0.27 to 1.00.
Exposure of human lymphocytes to 900 MHz radiofrequency from a commercial mobile phone for 30 minutes did not significantly impact DNA integrity.