6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.
Shield Your Body

Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

DNA & Genetic Damage

Human fibroblasts and 900 MHz radiofrequency radiation: evaluation of DNA damage after exposure and co-exposure to 3-Chloro-4-(dichloromethyl)-5-Hydroxy-2(5h)-furanone (MX).

No Effects Found

Sannino A, Di Costanzo G, Brescia F, Sarti M, Zeni O, Juutilainen J, Scarfì MR. · 2009

View Original Abstract
Share:

RF radiation at 900 MHz did not cause genotoxic or cytotoxic effects in human fibroblasts and did not enhance MX-induced DNA damage.

Plain English Summary

Summary written for general audiences

Researchers exposed human dermal fibroblasts from a healthy donor and a Turner's syndrome donor to 900 MHz RF radiation for 24 hours using a GSM-like signal at 1 W/kg, and Turner's syndrome fibroblasts were also exposed for 1 hour. For RF exposure alone, DNA damage was assessed with the alkaline comet assay and the cytokinesis-block micronucleus assay. RF radiation alone caused no genotoxic or cytotoxic effects in either cell line. MX increased DNA migration in the comet assay, but RF exposure did not enhance this MX-induced DNA damage.

Exposure Details

SAR
1 W/kg
Source/Device
900 MHz.
Exposure Duration
24 hours

Exposure Context

This study used 1 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 1 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 2 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

The aim of this study was to investigate DNA damage in human dermal fibroblasts from a healthy subject and from a subject affected by Turner's syndrome that were exposed for 24 h to radiofrequency (RF) radiation at 900 MHz.

The RF-radiation exposure was carried out alone or in combination with 3-chloro-4-(dichloromethyl)-5...

The results revealed no genotoxic and cytotoxic effects from RF radiation alone in either cell line....

Cite This Study
Sannino A, Di Costanzo G, Brescia F, Sarti M, Zeni O, Juutilainen J, Scarfì MR. (2009). Human fibroblasts and 900 MHz radiofrequency radiation: evaluation of DNA damage after exposure and co-exposure to 3-Chloro-4-(dichloromethyl)-5-Hydroxy-2(5h)-furanone (MX). Radiat Res 171:743-751, 2009.
Show BibTeX
@article{a_2009_human_fibroblasts_and_900_2928,
  author = {Sannino A and Di Costanzo G and Brescia F and Sarti M and Zeni O and Juutilainen J and Scarfì MR.},
  title = {Human fibroblasts and 900 MHz radiofrequency radiation: evaluation of DNA damage after exposure and co-exposure to 3-Chloro-4-(dichloromethyl)-5-Hydroxy-2(5h)-furanone (MX).},
  year = {2009},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/19580481/},
}
PubMed: 19580481

Cited By (29 papers)

Quick Questions About This Study

The study used human dermal fibroblasts from a healthy subject and from a subject with Turner's syndrome.
A GSM-like 900 MHz signal at 1 W/kg specific absorption rate was used for 24 hours, with Turner's syndrome cells also exposed for 1 hour.
The alkaline comet assay and the cytokinesis-block micronucleus assay were used to evaluate DNA damage.
No genotoxic or cytotoxic effects were observed from RF radiation alone in either cell line.
MX increased DNA migration in the comet assay, but RF exposure did not enhance this MX-induced DNA damage.