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EFFECT OF DIATHERMY (SHORT WAVE AND MICROWAVE) ON BONE GROWTH IN THE ALBINO RAT

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CHARLES S. WISE, BENJAMIN CASTLEMAN, ARTHUR L. WATKINS · 1949

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Single exposures to medical shortwave and microwave radiation altered bone growth in developing rats, suggesting electromagnetic fields can interfere with normal tissue development.

Plain English Summary

Summary written for general audiences

This 1949 study exposed growing rats to medical diathermy treatments (shortwave and microwave radiation) near their knee joints to see if these electromagnetic fields affected bone growth. The researchers found that single exposures to both 8-meter shortwave and 11-centimeter microwave frequencies caused observable changes in bone development. This early research demonstrated that electromagnetic radiation could interfere with normal growth processes in developing tissue.

Why This Matters

This pioneering study from 1949 deserves attention because it was among the first to document biological effects from electromagnetic radiation on developing tissue. The researchers found measurable impacts on bone growth from single exposures to frequencies still used in medical diathermy today. What makes this particularly relevant is that modern wireless devices operate at similar microwave frequencies, yet we're exposed continuously rather than in controlled medical settings. The fact that a single therapeutic exposure could alter bone development in growing rats raises important questions about chronic, low-level exposures from our wireless environment. While medical diathermy uses much higher power levels than consumer devices, the demonstrated biological impact on growing tissue suggests developing children may be particularly vulnerable to EMF effects.

Finding

When moderate soft-tissue injury was present immediately after exposure to either short-wave or microwave radiation, the subsequent effect on bone growth—shortening, deformity, partial or complete epiphyseal destruction, et cetera—did not always parallel the extent of the soft-tissue injury.

In their words

When moderate soft-tissue injury was present immediately after exposure to either short-wave or microwave radiation, the subsequent effect on bone growth—shortening, deformity, partial or complete epiphyseal destruction, et cetera—did not always parallel the extent of the soft-tissue injury.

Figures from the Original Paper

Diagrams extracted from the original research document.

diagramPage 1 - AI-described figure: A diagram illustrating the method of applying short-wave diathermy to the region of the knee in an albino rat.
chartPage 2 - Figure 2: Relation of short-wave diathermy to soft-tissue reaction.
diagramPage 5 - AI-described figure: Roentgenogram of rat (No. 12), thirty-six weeks after short-wave diathermy to right knee, showing obliteration of joint space and atrophy of epiphysis.
diagramPage 7 - AI-described figure: Photomicrographs showing the lower end of a rat's femur with normal epiphysis and diaphysis in Fig. 4, and two weeks after short-wave diathermy in Fig. 5.
diagramPage 9 - Fig. 7-A: Roentgenogram of rat (No. 44), eight weeks after microwave diathermy, showing destruction of femoral and tibial epiphyses and atrophy of patella.
photomicrographPage 10 - Fig. 7-C: Photomicrograph (×30) of lower portion of femur showing destruction of epiphysis, epiphyseal plate, and articular cartilage.

Exposure Information

Specific exposure levels were not quantified in this study.

Cite This Study
CHARLES S. WISE, BENJAMIN CASTLEMAN, ARTHUR L. WATKINS (1949). EFFECT OF DIATHERMY (SHORT WAVE AND MICROWAVE) ON BONE GROWTH IN THE ALBINO RAT.
Show BibTeX
@article{effect_of_diathermy_short_wave_and_microwave_on_bone_growth_in_the_albino_rat_g5584,
  author = {CHARLES S. WISE and BENJAMIN CASTLEMAN and ARTHUR L. WATKINS},
  title = {EFFECT OF DIATHERMY (SHORT WAVE AND MICROWAVE) ON BONE GROWTH IN THE ALBINO RAT},
  year = {1949},
  
  
}
No DOI on file for this study.

Quick Questions About This Study

Yes, this 1949 study found that single exposures to 8-meter shortwave diathermy caused observable changes in bone growth patterns in developing rat knee joints compared to unexposed control limbs.
Research showed that 11-centimeter microwave exposures altered bone development in growing rats. The study used approximately 50 animals and found measurable effects on bone length and tissue structure.
The study examined effects at varying time intervals after single diathermy exposures, suggesting bone growth changes could be detected relatively soon after electromagnetic field exposure to developing tissue.
Researchers tested both shortwave (8-meter wavelength) and microwave (11-centimeter wavelength) frequencies, representing the two main types of medical diathermy equipment available in the 1940s for therapeutic heating.
Yes, this 1949 study documented that electromagnetic radiation from medical diathermy equipment could cause changes in bone development, soft tissue reactions, and microscopic alterations in growing rat joints.