Effect of superposed electromagnetic noise on DNA damage of lens epithelial cells induced by microwave radiation
Authors not listed · 2008
Human lens epithelial cells exposed to radiofrequency fields at 3 and 4 W/kg showed increased DNA damage, and this effect was blocked by superposed 2 muT electromagnetic noise.
Plain English Summary
Researchers exposed human lens epithelial cells intermittently for 24 hours to radiofrequency fields at specific absorption rates of 1, 2, 3, and 4 W/kg. DNA damage measured by alkaline comet assay increased significantly at 3 and 4 W/kg, while double-strand breaks increased only at 4 W/kg. Intracellular reactive oxygen species levels rose significantly at 3 and 4 W/kg, and cells exposed to 4 W/kg showed G0/G1 cell cycle arrest. Apoptosis did not differ between exposed and sham groups, and all observed effects were blocked when the radiofrequency field was superposed with 2 muT electromagnetic noise.
Why This Matters
The authors concluded that microwave radiation induced DNA damage after G0/G1 arrest without leading to apoptosis, that increased reactive oxygen species may be associated with DNA damage, and that superposed electromagnetic noise blocks microwave radiation-induced DNA damage, ROS formation, and cell cycle arrest. The article was retracted in 2009.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{effect_of_superposed_electromagnetic_noise_on_dna_damage_of_lens_epithelial_cells_induced_by_microwave_radiation_ce935,
author = {Unknown},
title = {Effect of superposed electromagnetic noise on DNA damage of lens epithelial cells induced by microwave radiation},
year = {2008},
doi = {10.1167/iovs.07-1333},
}