Effect of weak combined static and extremely low-frequency alternating magnetic fields on tumor growth in mice inoculated with the Ehrlich ascites carcinoma
Authors not listed · 2009
Extremely weak alternating magnetic fields, combined with a static magnetic field, suppressed Ehrlich ascites carcinoma growth in mice.
Plain English Summary
Researchers found that an ultralow-frequency, extremely weak alternating magnetic field component showed marked antitumor activity when combined with a static magnetic field. The alternating field parameters that produced this effect were frequencies of 1, 4.4, or 16.5 Hz at intensities of 300, 100, or 150–300 nT, combined with a collinear static field of 42 µT. In mice with tumors, tumor tissue was practically absent after exposure to the weak magnetic fields, while control animals showed tumor invasion into surrounding tissues. In animals without tumors, no pathological deviations were observed after exposure to the weak magnetic field, suggesting the field was not toxic to healthy organisms.
Why This Matters
The study used mice inoculated with Ehrlich ascites carcinoma, a standard transplantable tumor model, to test whether specific weak magnetic field parameters could affect tumor growth. Exposure to the combined magnetic fields caused structural changes in some organs, including the liver and adrenal glands, which researchers suggested were probably due to the total degradation of the tumor tissue. The finding that healthy animals showed no pathological changes was presented as evidence that the magnetic field itself was not harmful to the organism.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{effect_of_weak_combined_static_and_extremely_low_frequency_alternating_magnetic_fields_on_tumor_growth_in_mice_inoculated_with_the_ehrlich_ascites_carcinoma_ce1403,
author = {Unknown},
title = {Effect of weak combined static and extremely low-frequency alternating magnetic fields on tumor growth in mice inoculated with the Ehrlich ascites carcinoma},
year = {2009},
doi = {10.1002/bem.20487},
}