Effects of 50- or 60-hertz, 100 microT magnetic field exposure in the DMBA mammary cancer model in Sprague-Dawley rats: possible explanations for different results from two laboratories
Authors not listed · 2000
Löscher's group in Germany reported that 50-Hz magnetic field exposure increased mammary tumors in rats, but Battelle in the United States could not replicate the finding.
Plain English Summary
Researchers from Löscher's group in Germany exposed Sprague-Dawley rats to 50-Hz magnetic fields at microtesla flux densities for 13 or 27 weeks using a DMBA breast cancer model. The exposure significantly increased mammary tumor development and growth in those experiments. A similar study by Battelle in the United States did not replicate the effect.
Why This Matters
The paper discusses differences between the two studies that might explain the discrepant results. Differences included rat substrain susceptibility to DMBA, diet and DMBA sources, environmental conditions, and magnetic field exposure metrics. The effects reported by Löscher's group were significant but weak. The authors also discuss the general difficulty of replicating such weak effects.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{effects_of_50_or_60_hertz_100_microt_magnetic_field_exposure_in_the_dmba_mammary_cancer_model_in_sprague_dawley_rats_possible_explanations_for_different_results_from_two_laboratories_ce1542,
author = {Unknown},
title = {Effects of 50- or 60-hertz, 100 microT magnetic field exposure in the DMBA mammary cancer model in Sprague-Dawley rats: possible explanations for different results from two laboratories},
year = {2000},
doi = {10.1289/EHP.00108797},
}