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Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Effects of different mobile phone UMTS signals on DNA, apoptosis and oxidative stress in human lymphocytes

No Effects Found

Gulati, S, Kosik, P, Durdik, M, Skorvaga, M., Jakl, L., Markova, E., Belyaev, I. · 2020

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The study found a small but statistically significant increase in DNA damage in human lymphocytes exposed to UMTS signals, with the strongest effect at 1977.0 MHz.

Plain English Summary

Summary written for general audiences

Researchers compared genotoxic effects of three UMTS frequency channels used by 3G phones (1923, 1947.47, and 1977 MHz) in human lymphocytes. Human lymphocytes were exposed for 1 hour and 3 hours and tested for ROS, DNA damage, TP53 mutations, preleukemic fusion genes, and apoptosis. No effects were seen on ROS, apoptosis, preleukemic fusion genes, or TP53 mutations at any frequency, though bulk RNA expression was inhibited. A small but statistically significant increase in DNA damage occurred depending on the UMTS frequency channel, with the maximum effect at 1977.0 MHz.

Why This Matters

Previous studies on radiofrequency radiation and DNA damage or reactive oxygen species have reported conflicting results. The authors note that earlier studies are not directly comparable because they used different exposure parameters, especially carrier frequency. The researchers conclude that each specific mobile communication signal should be tested in dedicated experiments to assess potential genotoxic effects from prolonged exposure.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1923-1977 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1923-1977 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Gulati, S, Kosik, P, Durdik, M, Skorvaga, M., Jakl, L., Markova, E., Belyaev, I. (2020). Effects of different mobile phone UMTS signals on DNA, apoptosis and oxidative stress in human lymphocytes.
Show BibTeX
@article{effects_of_different_mobile_phone_umts_signals_on_dna_apoptosis_and_oxidative_stress_in_human_lymphocytes_ce2390,
  author = {Gulati and S and Kosik and P and Durdik and M and Skorvaga and M. and Jakl and L. and Markova and E. and Belyaev and I.},
  title = {Effects of different mobile phone UMTS signals on DNA, apoptosis and oxidative stress in human lymphocytes},
  year = {2020},
  doi = {10.1016/j.envpol.2020.115632},
  
}

Quick Questions About This Study

The study compared genotoxic effects of three UMTS frequency channels (1923, 1947.47, and 1977 MHz) in human lymphocytes exposed for 1 hour and 3 hours.
No effects were found on ROS, apoptosis, preleukemic fusion genes, or TP53 mutations at any frequency, but a small statistically significant increase in DNA damage occurred with the maximum at 1977.0 MHz.
Exposure did not affect ROS, apoptosis, preleukemic fusion genes, or TP53 mutations, but it did inhibit bulk RNA expression and induced DNA damage in a frequency-dependent manner.
The maximum DNA damage effect was observed at the 1977.0 MHz UMTS frequency channel.
The authors recommend that each specific mobile communication signal should be tested in specially designed experiments to rule out genotoxic effects from prolonged exposure.