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Effects of Low-Intensity Microwave Radiation on Oxidant-Antioxidant Parameters and DNA Damage in the Liver of Rats

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Authors not listed · 2021

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Whole-body exposure to 1800 and 2100 MHz low-intensity microwave radiation increased oxidative stress markers and DNA damage while decreasing antioxidant status in the liver of rats.

Plain English Summary

Summary written for general audiences

Eighteen Sprague-Dawley male rats were divided into three groups of six each. Two groups were exposed to 1800 MHz or 2100 MHz microwave radiation for 2 hours per day over 7 months, while a third group served as sham control. After exposure, liver tissue was analyzed for DNA damage, malondialdehyde, 8-hydroxydeoxyguanosine, and total oxidant-antioxidant parameters. Both exposure frequencies significantly increased MDA, 8-OHdG, total oxidant status, oxidative stress index, and comet assay tail intensity, while decreasing total antioxidant status.

Why This Matters

The study aimed to examine the effects of low-intensity microwave radiation on DNA and oxidative damage in rat livers. The authors concluded that whole-body exposure to these frequencies can induce oxidative stress and lead to DNA strand breaks and oxidative DNA damage in the liver. The study was published in Bioelectromagnetics in 2021.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1800 MHz, 2100 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1800 MHz, 2100 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Unknown (2021). Effects of Low-Intensity Microwave Radiation on Oxidant-Antioxidant Parameters and DNA Damage in the Liver of Rats.
Show BibTeX
@article{effects_of_low_intensity_microwave_radiation_on_oxidant_antioxidant_parameters_and_dna_damage_in_the_liver_of_rats_ce2290,
  author = {Unknown},
  title = {Effects of Low-Intensity Microwave Radiation on Oxidant-Antioxidant Parameters and DNA Damage in the Liver of Rats},
  year = {2021},
  doi = {10.1002/bem.22315},
  
}

Quick Questions About This Study

The researchers measured malondialdehyde (MDA), 8-hydroxydeoxyguanosine (8-OHdG), total oxidant status, oxidative stress index, and total antioxidant status in liver tissue.
Both 1800 MHz and 2100 MHz exposure significantly increased comet assay tail intensity, indicating DNA strand breaks, and increased 8-OHdG, indicating oxidative DNA damage.
Total antioxidant status levels decreased significantly in both exposure groups.
The microwave exposure lasted for 7 months, with daily 2-hour sessions.