Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.
Effects of pulsed electromagnetic fields and N-acetylcysteine on transplantation of vitrified mouse ovarian tissue
Authors not listed · 2023
Combined NAC and pulsed electromagnetic field treatment increased follicle numbers and vascularization and showed a synergistic effect on angiogenesis and oxidative stress protection in vitrified mouse ovarian transplants.
Plain English Summary
Researchers randomly assigned adult female NMRI mice to five groups including fresh ovarian transplantation, vitrified transplantation, and vitrified transplantation with NAC, pulsed electromagnetic fields, or both. NAC, PEMF, and combined NAC+PEMF treatments significantly increased follicle numbers and vascularization in the transplanted tissue. The combined treatment also lowered malondialdehyde levels and demonstrated a synergistic effect on angiogenesis and oxidative stress protection.
Why This Matters
The relative expression of Fgf-2, Vegf, Tnf-α, Il-1β, and Il-6 was significantly elevated in the NAC, PEMF, and combined groups. NAC treatment alone significantly decreased total antioxidant capacity compared with the control group.
Show BibTeX
@article{effects_of_pulsed_electromagnetic_fields_and_n_acetylcysteine_on_transplantation_of_vitrified_mouse_ovarian_tissue_ce3941,
author = {Unknown},
title = {Effects of pulsed electromagnetic fields and N-acetylcysteine on transplantation of vitrified mouse ovarian tissue},
year = {2023},
doi = {10.1080/15368378.2023.2246503},
}