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Brain & Nervous System

Examining the effects of extremely low- frequency magnetic fields on cognitive functions and functional brain markers in aged mice

No Effects Found

Authors not listed · 2025

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Chronic exposure to 50 Hz ELF-MF at 1 mT for 12 weeks did not worsen age-related spatial memory decline or change hippocampal Alzheimer's-related protein markers in aged mice.

Plain English Summary

Summary written for general audiences

Researchers exposed aged mice to 50 Hz ELF-MF at 1 mT for 8 hours per day, 5 days per week for 12 weeks. Sham-exposed aged mice showed a significant age-related decline in spatial memory compared to young adult mice. Chronic ELF-MF exposure did not worsen this memory decline or change hippocampal levels of APP-695, Aβ(1−42), S100b, GFAP, or the pTau/Tau ratio.

Why This Matters

The authors suggest that chronic ELF-MF exposure does not aggravate aging, neuroinflammation, or Alzheimer's-related pathological pathways. They caution that results should not be directly extrapolated to older adults with comorbidities and recommend applying current exposure limits to sensitive locations.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 50 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 50 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Unknown (2025). Examining the effects of extremely low- frequency magnetic fields on cognitive functions and functional brain markers in aged mice.
Show BibTeX
@article{examining_the_effects_of_extremely_low_frequency_magnetic_fields_on_cognitive_functions_and_functional_brain_markers_in_aged_mice_ce4395,
  author = {Unknown},
  title = {Examining the effects of extremely low- frequency magnetic fields on cognitive functions and functional brain markers in aged mice},
  year = {2025},
  doi = {10.1038/s41598-025-93230-y},
  
}
DOI: 10.1038/s41598-025-93230-yPubMed: 40069380

Quick Questions About This Study

Aged mice were exposed to 50 Hz ELF-MF at 1 mT for 8 hours per day, 5 days per week for 12 weeks.
No, chronic ELF-MF exposure did not exacerbate the age-related decline in spatial memory.
No difference was observed in hippocampal expression of APP-695, Aβ(1−42), S100b, GFAP, or the pTau/Tau ratio between sham- and ELF-MF-exposed aged mice.
The authors suggest that chronic ELF-MF exposure does not aggravate aging, neuroinflammation, or promote Alzheimer's-related pathological pathways.
The authors caution that care should be taken in extrapolating these results to older adults with comorbidities and recommend applying current exposure limits to sensitive ELF-MF locations.