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Exposure to cell phone induce oxidative stress in mice preantral follicles during in vitro cultivation: An experimental study

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Authors not listed · 2019

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Cell phone exposure significantly lowered survival, antrum formation, ovulation rates, and antioxidant capacity in mice preantral follicles cultured in vitro, while raising MDA levels.

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Summary written for general audiences

Researchers isolated preantral follicles from 16 to 18 day-old NMRI mice and divided them into control and cell phone-exposed groups, culturing them for 12 days. Follicle diameters and rates of survival, antrum formation, ovulation, and metaphase II oocytes were all significantly lower in the cell phone-exposed group. Antioxidant enzyme activities (SOD, GPX, and CAT) and total antioxidant capacity were significantly lower in exposed follicles, while MDA levels were significantly higher.

Why This Matters

The study aimed to investigate the effect of cell phone exposure on the oxidative status of mice preantral follicles during in vitro culture. Researchers assessed both developmental outcomes and biochemical markers, measuring follicle size, survival, antral cavity formation, ovulation, and oocyte maturation alongside antioxidant and oxidative stress indicators. The researchers concluded that cell phone exposure compromised the developmental competence of mice preantral follicles by increasing oxidative stress.

Cite This Study
Unknown (2019). Exposure to cell phone induce oxidative stress in mice preantral follicles during in vitro cultivation: An experimental study.
Show BibTeX
@article{exposure_to_cell_phone_induce_oxidative_stress_in_mice_preantral_follicles_during_in_vitro_cultivation_an_experimental_study_ce2464,
  author = {Unknown},
  title = {Exposure to cell phone induce oxidative stress in mice preantral follicles during in vitro cultivation: An experimental study},
  year = {2019},
  doi = {10.18502/ijrm.v17i9.5099},
  
}

Quick Questions About This Study

The diameters and rates of survival, antrum formation, ovulation, and metaphase II oocytes of exposed follicles were significantly lower than those of the control group.
Researchers used 2,580 preantral follicles isolated from 50 NMRI mice.
The follicles were cultured for 12 days, after which ovulation was induced using human chorion gonadotropin.
Superoxide dismutase, glutathione peroxidase, and catalase activity were all significantly lower in the cell phone-exposed follicles compared with the control group.