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Effects of 1800-MHz radiofrequency fields on circadian rhythm of plasma melatonin and testosterone in male rats.

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Qin F, Zhang J, Cao H, Yi C, Li JX, Nie J, Chen LL, Wang J, Tong J · 2012

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Cell phone radiation disrupted natural hormone cycles in rats at exposure levels similar to extended phone use.

Plain English Summary

Summary written for general audiences

Researchers exposed male rats to cell phone frequency radiation (1800 MHz) for 2 hours daily over 32 days and measured how this affected their natural daily cycles of melatonin and testosterone production. The radiation disrupted both hormones' normal rhythms, with melatonin being more severely affected than testosterone. This suggests that radiofrequency exposure can interfere with the body's internal biological clock that regulates crucial hormones.

Why This Matters

This study reveals a concerning connection between radiofrequency exposure and hormonal disruption that goes beyond simple hormone level changes. The researchers found that 1800 MHz radiation - the same frequency used by many cell phones - actually disrupted the natural circadian rhythms of melatonin and testosterone production in male rats. What makes this particularly significant is that the exposure level (SAR of 0.58 W/kg) falls well within current safety limits and is comparable to what you might experience during extended cell phone use near your body. The disruption of melatonin's circadian rhythm is especially troubling because this hormone doesn't just regulate sleep - it's a powerful antioxidant that helps protect against cellular damage and supports immune function. When your body's natural hormone cycles are thrown off, it can cascade into broader health problems affecting everything from sleep quality to reproductive health to cancer risk.

Exposure Details

SAR
0.5762 W/kg
Power Density
0.208 µW/m²
Source/Device
1800 MHz
Exposure Duration
2 h/d for 32 days

Exposure Context

This study used 0.208 µW/m² for radio frequency:

This study used 0.5762 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 0.208 µW/m²Extreme Concern1,000 uW/m2FCC Limit10M uW/m2Effects observed in the Slight Concern range (Building Biology)FCC limit is 48,076,923x higher than this exposure level

Study Details

Radiofrequency fields (RF) at 1800 MHz are known to affect melatonin (MEL) and testosterone in male rats, but it remains to be determined whether RF affected circadian rhythm of these plasma hormones.

Male Sprague-Dawley rats were exposed to 1800-MHz RF at 208 μw/cm² power density (SAR: 0.5762 W/kg) ...

The results confirmed the existence of circadian rhythms in the synthesis of MEL and testosterone, b...

Data suggest that regulation of testosterone is controlled by MEL and that MEL is more sensitive to RF exposure.

Cite This Study
Qin F, Zhang J, Cao H, Yi C, Li JX, Nie J, Chen LL, Wang J, Tong J (2012). Effects of 1800-MHz radiofrequency fields on circadian rhythm of plasma melatonin and testosterone in male rats. J Toxicol Environ Health A.75(18):1120-1128, 2012.
Show BibTeX
@article{f_2012_effects_of_1800mhz_radiofrequency_1280,
  author = {Qin F and Zhang J and Cao H and Yi C and Li JX and Nie J and Chen LL and Wang J and Tong J},
  title = {Effects of 1800-MHz radiofrequency fields on circadian rhythm of plasma melatonin and testosterone in male rats.},
  year = {2012},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/22891885/},
}

Quick Questions About This Study

Researchers exposed male rats to cell phone frequency radiation (1800 MHz) for 2 hours daily over 32 days and measured how this affected their natural daily cycles of melatonin and testosterone production. The radiation disrupted both hormones' normal rhythms, with melatonin being more severely affected than testosterone. This suggests that radiofrequency exposure can interfere with the body's internal biological clock that regulates crucial hormones.