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Modulation of wireless (2.45 GHz)-induced oxidative toxicity in laryngotracheal mucosa of rat by melatonin

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Aynali G, Nazıroğlu M, Celik O, Doğan M, Yarıktaş M, Yasan H · 2013

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In rats exposed to 2.45 GHz Wi-Fi radiation, melatonin lowered lipid peroxidation and raised glutathione peroxidase activity.

Plain English Summary

Summary written for general audiences

Thirty-two male rats were divided into four groups, including a melatonin-treated group receiving 10 mg/kg/day. Rats in the exposure groups received 2.45 GHz radiation for 60 minutes daily for 28 days. Radiation exposure raised lipid peroxidation levels compared with controls. Melatonin treatment lowered lipid peroxidation and increased glutathione peroxidase activity. Reduced glutathione levels did not differ among groups.

Why This Matters

The study aimed to test whether melatonin could protect against oxidative stress from Wi-Fi radiation in the laryngotracheal mucosa. The authors concluded that melatonin appears to protect by inhibiting free radical formation and supporting the glutathione peroxidase system.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.45 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.45 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 2.45 GHz Duration: 60 min/day for 28 days

Study Details

The aim of this study was to investigate the possible protective role of melatonin on oxidative stress induced by Wi-Fi (2.45 GHz) EMR in laryngotracheal mucosa of rat.

For this purpose, 32 male rats were equally categorized into four groups, namely controls, sham cont...

The lipid peroxidation levels were significantly (p < 0.05) higher in the radiation-exposed groups t...

There is an apparent protective effect of melatonin on the Wi-Fi-induced oxidative stress in the laryngotracheal mucosa of rats by inhibition of free radical formation and support of the glutathione peroxidase antioxidant system.

Cite This Study
Aynali G, Nazıroğlu M, Celik O, Doğan M, Yarıktaş M, Yasan H (2013). Modulation of wireless (2.45 GHz)-induced oxidative toxicity in laryngotracheal mucosa of rat by melatonin Eur Arch Otorhinolaryngol. 270(5):1695-1700, 2013.
Show BibTeX
@article{g_2013_modulation_of_wireless_245_1614,
  author = {Aynali G and Nazıroğlu M and Celik O and Doğan M and Yarıktaş M and Yasan H},
  title = {Modulation of wireless (2.45 GHz)-induced oxidative toxicity in laryngotracheal mucosa of rat by melatonin},
  year = {2013},
  doi = {10.1007/s00405-013-2425-0},
  url = {https://link.springer.com/article/10.1007/s00405-013-2425-0},
}
DOI: 10.1007/s00405-013-2425-0

Cited By (29 papers)

Quick Questions About This Study

Rats were exposed to 2.45 GHz radiation for 60 minutes per day over 28 days.
Melatonin treatment significantly lowered lipid peroxidation compared with rats exposed to radiation alone.
Glutathione peroxidase activity was increased in melatonin-treated rats after radiation exposure.
Reduced glutathione levels did not change across any of the four groups.
Melatonin was administered at 10 mg/kg/day.