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The prophylactic effect of vitamin C on oxidative stress indexes in rat eyes following exposure to radiofrequency wave generated by a BTS antenna model.

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Jelodar G, Akbari A, Nazifi S. · 2013

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Radiofrequency wave exposure decreased antioxidant enzyme activity and increased malondialdehyde in rat eyes, and vitamin C supplementation improved enzyme activity and reduced malondialdehyde.

Plain English Summary

Summary written for general audiences

Researchers exposed adult male Sprague-Dawley rats to 900 MHz radiofrequency waves daily for 45 days and measured antioxidant enzymes and malondialdehyde in eye tissue. Radiofrequency wave exposure decreased glutathione peroxidase, superoxide dismutase, and catalase activity and increased malondialdehyde compared with controls. Vitamin C supplementation at 200 mg/kg per day improved antioxidant enzyme activity and reduced malondialdehyde compared with the test group.

Why This Matters

The researchers concluded that radiofrequency waves cause oxidative stress in the eyes and that vitamin C improves antioxidant enzyme activity and decreases malondialdehyde. Eye tissue was collected after sacrifice for enzyme and malondialdehyde assays.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 900 MHz Duration: 45 days

Study Details

This study was conducted to evaluate the effect of radiofrequency wave (RFW)-induced oxidative stress in the eye and the prophylactic effect of vitamin C on this organ by measuring the antioxidant enzymes activity including: glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT), and malondialdehyde (MDA).

Thirty-two adult male Sprague-Dawley rats were randomly divided into four experimental groups and tr...

The results indicate that exposure to RFW in the test group decreased antioxidant enzymes activity a...

It can be concluded that RFW causes oxidative stress in the eyes and vitamin C improves the antioxidant enzymes activity and decreases MDA

Cite This Study
Jelodar G, Akbari A, Nazifi S. (2013). The prophylactic effect of vitamin C on oxidative stress indexes in rat eyes following exposure to radiofrequency wave generated by a BTS antenna model. Int J Radiat Biol. 89(2):128-131, 2013.
Show BibTeX
@article{g_2013_the_prophylactic_effect_of_1652,
  author = {Jelodar G and Akbari A and Nazifi S.},
  title = {The prophylactic effect of vitamin C on oxidative stress indexes in rat eyes following exposure to radiofrequency wave generated by a BTS antenna model.},
  year = {2013},
  doi = {10.3109/09553002.2012.721051},
  url = {https://www.tandfonline.com/doi/abs/10.3109/09553002.2012.721051},
}

Cited By (30 papers)

Quick Questions About This Study

The study investigated the effect of radiofrequency wave exposure on oxidative stress in the eye and the protective effect of vitamin C.
Rats were exposed to 900 MHz radiofrequency waves daily for 45 days.
Radiofrequency wave exposure decreased antioxidant enzyme activity and increased malondialdehyde, while vitamin C supplementation improved enzyme activity and reduced malondialdehyde compared with the test group.
Vitamin C was administered at 200 mg/kg of body weight per day by gavage.
The researchers concluded that radiofrequency waves cause oxidative stress in the eyes and that vitamin C improves antioxidant enzyme activity and decreases malondialdehyde.