Oxidative stress and testicular damage induced by chronic exposure to 35.5 GHz millimeter wave radiation in male Wistar rats
Gautam R, Jha N, Tomar AK, Nirala JP, Arora T, Rajamani P · 2025
Chronic exposure to 35.5 GHz radiation for 2 hours daily over 60 days significantly decreased sperm viability and count, increased lipid peroxidation and DNA damage, and reduced antioxidant defenses in rat testes.
Plain English Summary
The exposed group received 35.5 GHz millimeter wave radiation for 2 hours per day over 60 days. Exposure significantly reduced sperm viability and count and caused morphometric changes in testicular tissue. Lipid peroxidation increased while superoxide dismutase, total sulfhydryl levels, and total antioxidant capacity decreased in exposed rats. DNA damage measured by comet assay was significantly increased in the exposed group.
Why This Matters
The study assessed sperm mitochondrial activity and multiple oxidative stress markers in testis homogenate. The authors suggest that oxidative mechanisms may underlie the observed testicular tissue damage. They conclude that chronic 35.5 GHz exposure may impair male reproductive function through oxidative stress.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{gautam_r_jha_n_tomar_ak_nirala_jp_arora_t_rajamani_p_ce2382,
author = {Gautam R and Jha N and Tomar AK and Nirala JP and Arora T and Rajamani P},
title = {Oxidative stress and testicular damage induced by chronic exposure to 35.5 GHz millimeter wave radiation in male Wistar rats},
year = {2025},
doi = {10.1111/andr.70107},
}