Gene expression in the mammary gland tissue of female Fischer 344 and Lewis rats after magnetic field exposure (50 Hz, 100 uT) for 2 weeks
Authors not listed · 2012
MF-exposed F344 rats showed altered gene expression in mammary tissue while Lewis rats did not.
Plain English Summary
Researchers exposed female Fischer 344 and Lewis rats to a 50 Hz, 100 μT magnetic field for two weeks. Whole genome microarray analysis of mammary gland tissue revealed decreased α-amylase, carbonic anhydrase 6, and lactoperoxidase gene expression, and increased cystatin E/M expression in exposed F344 rats but not in Lewis rats.
Why This Matters
The authors concluded that the gene expression changes in F344 rats may be involved in their susceptibility to magnetic fields. They suggested α-amylase as a promising target for further study because initial experiments indicate magnetic field exposure alters its functionality in breast tissue.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{gene_expression_in_the_mammary_gland_tissue_of_female_fischer_344_and_lewis_rats_after_magnetic_field_exposure_50_hz_100_ut_for_2_weeks_ce2090,
author = {Unknown},
title = {Gene expression in the mammary gland tissue of female Fischer 344 and Lewis rats after magnetic field exposure (50 Hz, 100 uT) for 2 weeks},
year = {2012},
doi = {10.3109/09553002.2012.660555},
}