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Gupta V, Srivastava R. 2.45 GHz microwave radiation induced oxidative stress: Role of inflammatory cytokines in regulating male fertility through estrogen receptor alpha in Gallus gallus domesticus

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Authors not listed · 2022

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Low-level 2.45 GHz microwave radiation exposure for 30 days decreased testicular weight and seminiferous tubule diameter in immature male chickens.

Plain English Summary

Summary written for general audiences

Researchers exposed two-week-old immature male chickens to non-thermal low-level 2.45 GHz microwave radiation for two hours per day over 30 days. Exposed chickens showed decreased testicular weight, volume, and gonado-somatic index, as well as a substantial reduction in seminiferous tubule diameter. Radiation exposure increased oxidative stress parameters, increased IL-1β immunoreactivity, decreased IL-10 immunoreactivity, and reduced ERα expression in testes.

Why This Matters

The authors conclude that testes are vulnerable to free radical damage and become an easy target for microwave-induced oxidative and inflammatory stress. They suggest that this may cause male infertility in chicks through downregulation of ER-α in the testis.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.45 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.45 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Unknown (2022). Gupta V, Srivastava R. 2.45 GHz microwave radiation induced oxidative stress: Role of inflammatory cytokines in regulating male fertility through estrogen receptor alpha in Gallus gallus domesticus.
Show BibTeX
@article{gupta_v_srivastava_r_245_ghz_microwave_radiation_induced_oxidative_stress_role_of_inflammatory_cytokines_in_regulating_male_fertility_through_estrogen_receptor_alpha_in_gallus_gallus_domesticus_ce2396,
  author = {Unknown},
  title = {Gupta V, Srivastava R. 2.45 GHz microwave radiation induced oxidative stress: Role of inflammatory cytokines in regulating male fertility through estrogen receptor alpha in Gallus gallus domesticus},
  year = {2022},
  doi = {10.1016/j.bbrc.2022.09.009},
  
}

Quick Questions About This Study

Two-week-old immature male chickens were exposed to non-thermal low-level 2.45 GHz microwave radiation for two hours per day for 30 days at a power density of 0.1264 mw/cm2 and SAR of 0.9978 W/kg.
Exposed chickens had decreased testicular weight, volume, and gonado-somatic index, and a substantial reduction in seminiferous tubule diameter.
Radiation increased oxidative stress parameters, increased IL-1β immunoreactivity, and decreased IL-10 immunoreactivity in testes.
A substantial reduction in ERα expression was observed in exposed testes by Western blotting.