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Amelioration and Immuno-modulation by Ashwagandha on Wi-fi Induced Oxidative Stress in Regulating Reproduction Via Estrogen Receptor Alpha in Male Japanese Quail

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Gupta V, Srivastava R · 2025

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Ashwagandha supplementation ameliorated Wi-Fi radiation-induced reproductive dysfunction in male quail by restoring oxidative balance and reducing inflammatory responses.

Plain English Summary

Summary written for general audiences

This study examined the effects of 2.4 GHz Wi-Fi radiation exposure on reproductive function and oxidative stress in male Japanese quail, and tested whether Ashwagandha root extract could mitigate these effects. Wi-Fi exposure reduced testicular weight, testosterone levels, and sperm count while increasing oxidative stress and inflammatory markers, whereas Ashwagandha treatment reversed these changes by restoring antioxidant activity, testosterone levels, and immune balance.

Why This Matters

This is an animal model study using Japanese quail at relatively high specific absorption rates (SAR = 0.9978 W/kg). The findings on oxidative stress and inflammation mechanisms are mechanistically detailed, though translating results from avian models to human health effects requires considerable caution and additional research.

Exposure Information

Specific exposure levels were not quantified in this study.

Cite This Study
Gupta V, Srivastava R (2025). Amelioration and Immuno-modulation by Ashwagandha on Wi-fi Induced Oxidative Stress in Regulating Reproduction Via Estrogen Receptor Alpha in Male Japanese Quail.
Show BibTeX
@article{gupta_v_srivastava_r_ce2398,
  author = {Gupta V and Srivastava R},
  title = {Amelioration and Immuno-modulation by Ashwagandha on Wi-fi Induced Oxidative Stress in Regulating Reproduction Via Estrogen Receptor Alpha in Male Japanese Quail},
  year = {2025},
  doi = {10.1080/19490976.2025.2492378},
  
}
DOI: 10.1080/19490976.2025.2492378PubMed: 39806168

Quick Questions About This Study

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