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Amelioration and Immuno-modulation by Ashwagandha on Wi-fi Induced Oxidative Stress in Regulating Reproduction Via Estrogen Receptor Alpha in Male Japanese Quail

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Gupta V, Srivastava R · 2025

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Ashwagandha treatment counteracted Wi-Fi radiation-induced reproductive damage in male quail by modulating oxidative stress, inflammatory cytokines, and hormone-related gene expression.

Plain English Summary

Summary written for general audiences

This study examined the effects of 2.4 GHz Wi-Fi radiation exposure on male Japanese quail reproductive function, oxidative stress markers, and immune response over 30 days. The researchers found that Wi-Fi exposure reduced testicular function and sperm count while increasing oxidative stress and inflammatory markers, and that oral administration of Ashwagandha root extract reversed these effects by restoring antioxidant balance, reducing inflammation, and enhancing estrogen receptor alpha expression.

Why This Matters

This study uses an avian model to investigate potential reproductive and immunological effects of radiofrequency electromagnetic fields. The findings are specific to this experimental system and would require further validation in other models and species before broader implications could be established.

Exposure Information

Specific exposure levels were not quantified in this study.

Cite This Study
Gupta V, Srivastava R (2025). Amelioration and Immuno-modulation by Ashwagandha on Wi-fi Induced Oxidative Stress in Regulating Reproduction Via Estrogen Receptor Alpha in Male Japanese Quail.
Show BibTeX
@article{gupta_v_srivastava_r_ce3703,
  author = {Gupta V and Srivastava R},
  title = {Amelioration and Immuno-modulation by Ashwagandha on Wi-fi Induced Oxidative Stress in Regulating Reproduction Via Estrogen Receptor Alpha in Male Japanese Quail},
  year = {2025},
  doi = {10.1080/19490976.2025.2492378},
  
}
DOI: 10.1080/19490976.2025.2492378PubMed: 39806168

Quick Questions About This Study

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