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Long term impairment of cognitive functions and alterations of NMDAR subunits after continuous microwave exposure

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Wang H, Tan S, Xu X, Zhao L, Zhang J, Yao B, Gao Y, Zhou H, Peng R. · 2017

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Microwave radiation caused lasting memory and learning problems in rats at power levels similar to close wireless device exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed rats to microwave radiation at 2.856 GHz for six minutes daily over six weeks. Higher exposure levels caused lasting learning and memory problems, abnormal brain waves, and physical brain damage that persisted for months after exposure ended.

Why This Matters

This research provides compelling evidence that microwave radiation exposure can cause lasting cognitive damage, with effects persisting up to a year after exposure ended. The power densities used (2.5-10 mW/cm²) are within ranges that people can encounter from wireless devices in close proximity, making these findings directly relevant to everyday EMF exposure scenarios. What makes this study particularly significant is its demonstration of dose-dependent effects and the identification of specific molecular mechanisms (NMDAR receptor changes) underlying the cognitive impairment. The reality is that this adds to a growing body of evidence showing microwave radiation can fundamentally alter brain structure and function, contradicting industry claims that non-thermal EMF exposure is harmless.

Exposure Details

Power Density
0, 2.5, 5 and 10 µW/m²
Source/Device
2.856 GHz
Exposure Duration
6 min/day, 5 days/week and up to 6 weeks

Exposure Context

This study used 0, 2.5, 5 and 10 µW/m² for radio frequency:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 0, 2.5, 5 and 10 µW/m²Extreme Concern1,000 uW/m2FCC Limit10M uW/m2Effects observed in the Slight Concern range (Building Biology)FCC limit is 4,000,000x higher than this exposure level

Study Details

The long term effects of continuous microwave exposure cannot be ignored for the simulation of the real environment and increasing concerns about the negative cognitive effects of microwave exposure.

In this study, 220 male Wistar rats were exposed by a 2.856 GHz radiation source with the average po...

Results found that the rats in the 10 mW/cm2 group showed the decline of spatial learning and memory...

Our findings suggested that the continuous microwave exposure could cause the dose-dependent long term impairment of spatial learning and memory, the abnormalities of EEG and the hippocampal structure injuries. The decrease of NMDAR key subunits and phosphorylation of NR 2B might contribute to the cognitive impairment.

Cite This Study
Wang H, Tan S, Xu X, Zhao L, Zhang J, Yao B, Gao Y, Zhou H, Peng R. (2017). Long term impairment of cognitive functions and alterations of NMDAR subunits after continuous microwave exposure Physiol Behav. 181:1-9, 2017.
Show BibTeX
@article{h_2017_long_term_impairment_of_199,
  author = {Wang H and Tan S and Xu X and Zhao L and Zhang J and Yao B and Gao Y and Zhou H and Peng R.},
  title = {Long term impairment of cognitive functions and alterations of NMDAR subunits after continuous microwave exposure},
  year = {2017},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0031938417302706},
}

Quick Questions About This Study

Researchers exposed rats to microwave radiation at 2.856 GHz for six minutes daily over six weeks. Higher exposure levels caused lasting learning and memory problems, abnormal brain waves, and physical brain damage that persisted for months after exposure ended.