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Oxidative Stress

Evaluation of parameters of oxidative stress after in vitro exposure to FMCW- and CDMA-modulated radiofrequency radiation fields.

No Effects Found

Hook, G. J., Spitz, D. R., Sim, J. E., Higashikubo, R., Baty, J. D., Moros, E. G. and Roti Roti, J. L. · 2004

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Cell phone radiation at 0.8 W/kg showed no oxidative stress effects in immune cells after 20+ hours of exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed mouse immune cells to cell phone radiation at 835-847 MHz for over 20 hours to test whether radiofrequency signals cause oxidative stress (cellular damage from harmful molecules). They found no evidence that either FMCW or CDMA modulated signals at 0.8 W/kg caused oxidative stress, cellular damage, or changes in the cells' natural antioxidant defenses. The study suggests that cell phone-type radiation at these levels does not trigger the cellular stress responses that can lead to health problems.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 847.7 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 847.7 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 835.62, 847.74 MHz Duration: 20-22 hours

Study Details

The goal of this study was to determine whether radiofrequency (RF) radiation is capable of inducing oxidative stress or affecting the response to oxidative stress in cultured mammalian cells.

The two types of RF radiation investigated were frequency-modulated continuous-wave with a carrier f...

The results of these studies indicated that FMCW- and CDMA-modulated RF radiation did not alter para...

Cite This Study
Hook, G. J., Spitz, D. R., Sim, J. E., Higashikubo, R., Baty, J. D., Moros, E. G. and Roti Roti, J. L. (2004). Evaluation of parameters of oxidative stress after in vitro exposure to FMCW- and CDMA-modulated radiofrequency radiation fields. Radiat. Res. 162, 497–504, 2004.
Show BibTeX
@article{hook_2004_evaluation_of_parameters_of_3091,
  author = {Hook and G. J. and Spitz and D. R. and Sim and J. E. and Higashikubo and R. and Baty and J. D. and Moros and E. G. and Roti Roti and J. L.},
  title = {Evaluation of parameters of oxidative stress after in vitro exposure to FMCW- and CDMA-modulated radiofrequency radiation fields.},
  year = {2004},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/15624304/},
}
PubMed: 15624304

Cited By (56 papers)

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Quick Questions About This Study

No, a 2004 study found that 847 MHz CDMA radiation at 0.8 W/kg did not cause oxidative stress in mouse immune cells after 20+ hours of exposure. The researchers detected no cellular damage, harmful molecule buildup, or changes in natural antioxidant defenses.
Research shows 835 MHz FMCW signals at 0.8 W/kg do not damage immune system cells. A controlled study exposed mouse J774.16 immune cells for over 20 hours and found no toxicity, cellular stress, or impaired antioxidant function.
Mouse immune cells showed no damage after more than 20 hours of continuous 847 MHz radiofrequency exposure at cell phone power levels. The 2004 study found no oxidative stress, cellular toxicity, or antioxidant system disruption during extended exposure periods.
No, 0.8 W/kg radiofrequency radiation does not trigger cellular antioxidant responses. Research on mouse immune cells found that both FMCW and CDMA modulated signals at this power level caused no changes in natural antioxidant defenses or stress indicators.
Both FMCW and CDMA modulation types appear equally safe for cells based on laboratory evidence. A 2004 study found neither modulation type at 835-847 MHz frequencies caused oxidative stress, cellular damage, or toxicity in mouse immune cells.