Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.
Evaluation of Parameters of Oxidative Stress after In Vitro Exposure to FMCW- and CDMA-Modulated Radiofrequency Radiation Fields.
Hook, G. J., Spitz, D. R., Sim, J. E., Higashikubo, R., Baty, J. D., Moros, E. G. and Roti Roti, J. L. · 2004
View Original AbstractFMCW- and CDMA-modulated RF radiation did not alter oxidative stress parameters in J774.16 cells.
Plain English Summary
Researchers exposed J774.16 mouse macrophage cells to FMCW radiation at 835.62 MHz and CDMA radiation at 847.74 MHz for 20–22 hours at a specific absorption rate of 0.8 W/kg. Cells were stimulated with γ-interferon and bacterial lipopolysaccharide before exposure. The results indicated that FMCW- and CDMA-modulated RF radiation did not alter parameters indicative of oxidative stress in J774.16 cells.
Why This Matters
FMCW- and CDMA-modulated fields did not alter the level of intracellular oxidants, accumulation of GSSG, or induction of antioxidant defenses in IFN/LPS-stimulated cells. No change in toxicity was observed in J774.16 cells after either optimal or suboptimal stimulation. Oxidative stress was evaluated by measuring oxidant levels, antioxidant levels, oxidative damage, and nitric oxide production.
Exposure Details
- SAR
- 0.8 W/kg
- Source/Device
- 835.62 MHz (FMCW) and 847.74 MHz (CDMA)
- Exposure Duration
- 20–22 h
Exposure Context
This study used 0.8 W/kg for SAR (device absorption):
- 2x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
The goal of this study was to determine whether radiofrequency (RF) radiation is capable of inducing oxidative stress or affecting the response to oxidative stress in cultured mammalian cells.
The two types of RF radiation investigated were frequency-modulated continuous-wave with a carrier f...
The results of these studies indicated that FMCW- and CDMA-modulated RF radiation did not alter para...
Show BibTeX
@article{hook_2004_evaluation_of_parameters_of_2877,
author = {Hook and G. J. and Spitz and D. R. and Sim and J. E. and Higashikubo and R. and Baty and J. D. and Moros and E. G. and Roti Roti and J. L.},
title = {Evaluation of Parameters of Oxidative Stress after In Vitro Exposure to FMCW- and CDMA-Modulated Radiofrequency Radiation Fields.},
year = {2004},
url = {https://meridian.allenpress.com/radiation-research/article-abstract/162/5/497/149861/Evaluation-of-Parameters-of-Oxidative-Stress-after},
}