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Free Radical Release and HSP70 Expression in Two Human Immune-Relevant Cell Lines after Exposure to 1800 MHz Radiofrequency Radiation.

No Effects Found

Lantow M, Schuderer J, Hartwig C, Simko M. · 2006

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No significant differences in free radical production were detected after RF EMF exposure, and no significant effects on HSP70 expression were found.

Plain English Summary

Summary written for general audiences

Heat and PMA treatment significantly increased superoxide radical anions and ROS production in Mono Mac 6 cells. No significant differences in free radical production were detected after RF EMF exposure compared to controls. The GSM-DTX signal at 2 W/kg showed a significant difference versus sham due to a decreasing sham value, but this difference disappeared when compared to incubator controls. No significant effects on HSP70 expression were detected after RF EMF exposures.

Why This Matters

The study aimed to test whether 1800 MHz RF EMF exposure causes free radical production or HSP70 expression in human immune-relevant cell lines. The researchers examined HSP70 expression as a possible inhibitor of free radical production after various RF EMF exposures.

Exposure Details

SAR
0.5, 1.0, 1.5 and 2.0 W/kg
Source/Device
1800 MHz

Exposure Context

This study used 0.5, 1.0, 1.5 and 2.0 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.5, 1.0, 1.5 and 2.0 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 3 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1.80 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1.80 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

The goal of this study was to investigate whether radiofrequency (RF) electromagnetic-field (EMF) exposure at 1800 MHz causes production of free radicals and/or expression of heat-shock proteins (HSP70) in human immune-relevant cell systems.

Human Mono Mac 6 and K562 cells were used to examine free radical release after exposure to incubato...

Heat and PMA treatment induced a significant increase in superoxide radical anions and in ROS produc...

To determine the involvement of heat-shock proteins as a possible inhibitor of free radical production, we investigated the HSP70 expression level after different RF EMF exposures; no significant effects were detected

Cite This Study
Lantow M, Schuderer J, Hartwig C, Simko M. (2006). Free Radical Release and HSP70 Expression in Two Human Immune-Relevant Cell Lines after Exposure to 1800 MHz Radiofrequency Radiation. Radiat Res. 165(1):88-94, 2006.
Show BibTeX
@article{m_2006_free_radical_release_and_2882,
  author = {Lantow M and Schuderer J and Hartwig C and Simko M.},
  title = {Free Radical Release and HSP70 Expression in Two Human Immune-Relevant Cell Lines after Exposure to 1800 MHz Radiofrequency Radiation.},
  year = {2006},
  
  url = {https://meridian.allenpress.com/radiation-research/article-abstract/165/1/88/42290/Free-Radical-Release-and-HSP70-Expression-in-Two},
}

Quick Questions About This Study

Human Mono Mac 6 and K562 cells were used.
Continuous-wave and GSM modulations (GSM-non DTX, GSM-DTX, GSM-Talk) were tested at SARs of 0.5, 1.0, 1.5, and 2.0 W/kg.
No significant differences in free radical production were detected after RF EMF exposure compared to controls.
The GSM-DTX signal at 2 W/kg showed a significant difference versus sham due to a decreasing sham value, but this difference disappeared when compared to incubator controls.
No significant effects on HSP70 expression were detected after RF EMF exposures.