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Oxidative Stress

Free radical release and HSP70 expression in two human immune-relevant cell lines after exposure to 1800 MHz Radiofrequency Radiation.

No Effects Found

Lantow M, Schuderer J, Hartwig C, Simko M. · 2006

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Cell phone radiation up to 2.0 W/kg did not trigger free radical production in immune cells, suggesting this damage pathway may not occur at typical phone exposure levels.

Plain English Summary

Summary written for general audiences

Researchers exposed human immune cells to cell phone radiation at 1800 MHz (the frequency used by GSM networks) to see if it would trigger the production of harmful free radicals or stress proteins. Even at high exposure levels up to 2.0 W/kg, the radiation did not cause any significant increase in free radical production or stress protein expression in the cells. This suggests that cell phone radiation at these levels may not trigger the type of cellular damage that free radicals can cause.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1.80 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1.80 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 1800 MHz

Study Details

The goal of this study was to investigate whether radiofrequency (RF) electromagnetic-field (EMF) exposure at 1800 MHz causes production of free radicals and/or expression of heat-shock proteins (HSP70) in human immune-relevant cell systems.

Human Mono Mac 6 and K562 cells were used to examine free radical release after exposure to incubato...

Heat and PMA treatment induced a significant increase in superoxide radical anions and in ROS produc...

This difference disappeared when data were compared to the incubator controls. To determine the involvement of heat-shock proteins as a possible inhibitor of free radical production, we investigated the HSP70 expression level after different RF EMF exposures; no significant effects were detected.

Cite This Study
Lantow M, Schuderer J, Hartwig C, Simko M. (2006). Free radical release and HSP70 expression in two human immune-relevant cell lines after exposure to 1800 MHz Radiofrequency Radiation. Radiat Res. 165(1):88-94, 2006.
Show BibTeX
@article{m_2006_free_radical_release_and_3176,
  author = {Lantow M and Schuderer J and Hartwig C and Simko M.},
  title = {Free radical release and HSP70 expression in two human immune-relevant cell lines after exposure to 1800 MHz Radiofrequency Radiation.},
  year = {2006},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/16392966/},
}
PubMed: 16392966

Cited By (83 papers)

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Quick Questions About This Study

No, a 2006 study found that 1800 MHz GSM radiation did not cause significant free radical production in human immune cells, even at high exposure levels up to 2.0 W/kg. The radiation failed to trigger the type of cellular damage that free radicals typically cause in immune system cells.
Research shows that cell phone radiation at 2 W/kg does not significantly increase HSP70 stress protein expression in human immune cells. The 2006 study found no detectable effects on heat shock protein levels after exposure to 1800 MHz radiofrequency radiation.
No, GSM frequencies at 1800 MHz do not increase superoxide radical production in human immune cells. While heat treatment caused significant increases in these harmful radicals, cell phone radiation exposure showed no such effects in laboratory testing.
Studies indicate that 1800 MHz radiation is not harmful to Mono Mac 6 immune cells at exposure levels up to 2.0 W/kg. The radiation did not increase free radical production or stress protein expression, suggesting minimal cellular impact on these immune system cells.
Research found that GSM-DTX signals at 2 W/kg do not cause oxidative damage in human immune cells. Any apparent differences in free radical production disappeared when compared to proper control conditions, indicating no real cellular harm from the exposure.